67 books like Spillover

Barry’s dramatic historical account of the 1918 influenza pandemic has been called “fascinating,” “brilliant,” “sobering,” and “terrifying” by numerous reviewers.

It is a piece of history, the worst public health disaster in the century before COVID-19, that should have helped succeeding generations to take pandemic preparedness more seriously. It should have enhanced our understanding that during such a crisis, science must lead the way. Despite all that we did learn from the great influenza of 1918, we were unable to avoid many of the mistakes made when our leaders too often shunned the advice of science and made the COVID-19 pandemic political.

This book informed and influenced me greatly. It inspired me to see the need for and the importance of recording and learning from our experiences a century later.

Only dogged research could unearth the story of how one Black woman’s death – and the harvesting of her cells – could change the course of medical research.

It is a story of how some innocuous biological matter could grow into a hothouse of excess. Pharma companies enriched themselves reproducing the cells of Henrietta Lacks but did little or nothing for the family who lost their matriarch.  

For me, this book unleashed the idea of shaping deep research into a story can change our view of society.

After reading David Hackett’s book, I cannot think of American society in the same way again. The United States is touted as the great melting pot, but we all know that cultural nuggets may refuse to mix thoroughly with the rest. What I learned from this book is that even within white Angle-America, behavior patterns that differentiated Englishmen hundreds of years ago persist in America today. This book is not about red states and blue states, but it is impossible to read it and not see the connections.

Hackett traces the colonial immigration of four populations who settled the colonies–New England Puritans, Quakers and others of the Middle Colonies, Cavaliers of the South, and the Scotch-Irish of the Appalachian back-country. They differed significantly in geographic origins, speech, architecture, family structure and values, gender roles, food, dress, work patterns, and the concept of freedom.

Those differences are still with us and… show more.

Is it nature or nurture that makes a person? Well, it depends on the trait. Many things (e.g., number of noses or biological sex) are genetically determined. Other traits like IQ are about 50/50 genes and environment. Still others, like language, are entirely environmental. 

Humans are fascinated by genetic determinism and its contributions to race, gender, feeble-mindedness, disease. Witness the popularity of 23 and Me. Zimmer’s wonderful book gives an even-handed and sometimes brave account of the history of our obsession with heredity and some of the terrible things that have emerged from it: eugenics, forced sterilization, concern about human "mongrels," the concept of racial purity.

I was fascinated by the details he dug up, explaining the life experiences of individual people who fell afoul of government programs to "improve" the human population. 

One of the things I love about this book is that it takes us back to 1831, when Darwin was just an obscure 22-year-old, following his passion for natural history by embarking on what would be a five-year circumnavigation of the globe. I get the impression he would be a fascinating, if exhausting, travelling companion since he is relentlessly curious about everything and everyone he sees.

My favorite chapter is on the Galápagos archipelago because Darwin is trying to do descriptive justice to the unearthly basaltic lava landscape, as well as unique flora and fauna. I find there’s an immediacy to his writing which gives me the sense of looking over his shoulder as he describes all the elements of unfamiliar ecosystems, trying to puzzle out what they can possibly mean. 

It is hard to believe that Matt Ridley’s grand tour of the human genome was published back in 1999. Yet even today, more than two decades later, Ridley’s engaging, chromosome by chromosome investigation of our genetic make-up remains a marvel that has never been equaled. From the genes that enable the most basic chemical processes in our cells to those that determine our height and eye color, the mysterious “junk DNA” that lives between our genes, and speculation about the ways that genes affect personality, behavior, and society, Ridley brings science to life in this engaging and timeless book.

This is one of those books that you have to read either alone or among tolerant friends, because every few pages you’ll be moved to read some bit of it aloud to everyone around you. Alondra Nelson is a brilliant sociologist of science and technology, and this book tells the story of how genetic science and racial politics intersect, sometimes in surprising ways. I love how this book intertwines cultural and political history with clear-eyed analysis of genomics, genealogy, and the life sciences—it’s a great example of how to write about the human stakes of scientific research and innovation.

More than thirty years ago, when I was conducting research on the psychology of altruism and moral development, a biologist recommended that I read The Selfish Gene. 

Reading Dawkins’ book caused me to change my theoretical orientation completely.  It enabled me to see that if I wanted to understand altruism and morality, I needed to understand how the genes that guide the construction of the mental mechanisms that cause us to help others evolved. 

Although the title of the book implies that we are selfish by nature, the contents explain how selfish genes can guide the development of unselfish animals.  

This is a fascinating book that gives clarity to a difficult topic: how does our brain make decisions? I taught neuroscience before I retired, and I understand that when the semester turns to the cerebrum, details fade into vague and general statements. I confess to cribbing lecture notes from Sapolsky’s popular book because he explains things much more effectively than any textbook. Of course, our behaviors are influenced by immediate circumstances and by past experiences. And, yes, ancestral genetic patterns and molecular dynamics within the neurons also play a role. But so does something as simple as fatigue–and we all know that making lots of decisions can be exhausting and leave us as much in need of food and rest as digging a ditch. Now, I can justify an afternoon nap even if I have only been working at my desk all morning.

Richard Sapolsky is known for his popular… show more.

During the flu pandemic of 1918, the author, Katherine Anne Porter, became deathly ill but recovered. Published over twenty years later, Pale Horse, Pale Rider is her fictionalized account about falling in love with a soldier during the war, then fighting to survive the influenza outbreak. I love that Porter drew from her own experience to write this short novel. (She disliked the term novella.) Pale Horse, Pale Rider is a beautifully written story about a devastating disease.