The most recommended books on genes

The biggest strength of the gene’s-eye view is that it helps us make sense of things that seem impossible to understand from the perspective of individual organisms. One example is selfish genetic elements. These are genes that in one way or another have hijacked the system by which genes are replicated and passed on to the next generation. This ability allow them to spread in a population, even if they are harmful to the organism that carries them. I was given Burt and Trivers's book as an undergraduate by the professor who would later become my PhD advisor. That was over ten years ago, but every time I pick up this book I am reminded of how awestruck I was. Selfish genetic elements and genetic conflicts are a weird and wonderful world and Genes in Conflict is the best guide there is.  

This book about a tiny creature different from the rest touched my heart in a big way.

Like the scientist whose discovery inspired this book, I pay attention to small things. What small thing did the scientist notice? A snail shell that spiraled the opposite way of most snails–left instead of right. This one-in-a-million snail had inverted organs–his heart and other organs were on the right side, and he couldn’t reproduce without a mate who also had inverted organs.

Through crowdsourcing, two snails with right hearts were found–and eventually, baby snails were born!

Genetics, diversity, evolution, and love all fit into this book, tenderly and beautifully told in sparse language that somehow helped me understand these big concepts–and encouraged me to look for and appreciate the diversity in our world.

When I read Michael Crichton’s Next, my first thought was that we’re entering a dangerous time with our ability to manipulate the genomes of many different species.

The central message is about the possible negative ramifications of manipulating the DNA of humans and other animal species and even the creation of transspecies. Crichton leads us through diverse stories of corporate greed to the life and death struggles of others just wanting a cure for cancer.

Crichton does a masterful job of tying the different agendas into a compelling, interwoven narrative. 

When I read Richard Dawkins’s The Extended Phenotype I knew I wanted to become an evolutionary biologist. The book is the most ambitious articulation of the gene’s-eye view (a work of ‘unabashed advocacy’, as Dawkins put it). Less famous that The Selfish Gene, it also includes responses to the criticisms that The Selfish Gene received, which also made debates in theoretical biology seem so exciting. In many ways, that excitement has never left me. 

In his seminal The Selfish Gene, Richard Dawkins suggested that humans (and all other living organisms) exist to further the evolutionary fitness of the self-replicating information packets (“genes”) carried in our DNA – not the other way around.

In the closing section of his book, Dawkins theorized that a similar dynamic might hold true in cultural evolution, playing out through another type of self-replicating information packet, which he termed “memes”.

Some twenty years later, as the dawn of the Internet Age was giving new relevance to this idea, scholar Susan Blackmore took it up and ran with it, essentially singlehandedly creating the new academic field of “memetics” with the publication of The Meme Machine in 1999.

I sobbed my way through this one! I was a few chapters in when I discovered that it was a sequel to The Last Days of Rabbit Hayes, but I was so invested by then that I couldn’t stop and go back.

Anna McPartlin has the enviable skill of combining comedy and tragedy to great effect. The Hayes family are a mess of grief and confusion and misplaced blame, but their love for one another, and their wonderful humour, meant that I took them to my heart immediately.

A book that makes me laugh out loud one minute and blub like a baby the next is always a winner for me. I would read anything that this author chose to write. (I read Rabbit Hayes immediately afterwards and loved that, too!

I love this book because it turns the most impactful science discovery of the 21st century–CRISPR gene editing–into a page-turner. Isaacson combines a biography of Jennifer Doudna, who shared the 2020 Nobel Prize in Chemistry with Emmanuelle Charpentier, with lucid accounts of the science and sequence of research breakthroughs that underlie CRISPR editing, as well as the intrigues and jockeying among powerful scientists and personalities vying for prizes and patents on the technology.

I came through this book to appreciate the enormous potential of CRISPR gene editing for good (curing hereditary diseases) and not-so-good (designer babies or, in the words of Vladimir Putin, “a soldier, an individual who can fight without fear or compassion, mercy or pain”). CRISPR promises to make human selection as important as natural selection in the evolution of many species, including humans.

Evolution’s Rainbow made me happy and excited because I write about sexuality and gender in my books. In a time when the LGBTQ+ community is being attacked, especially by criminalizing transgender people, this scientifically based book by a trans woman is a cause for celebration.

She presents numerous compelling examples from nature demonstrating that homosexuality and gender diversity/mutability are not uncommon. In later parts of the book, Roughgarden examines the various genetic and physiological origins of transgenderism in humans and the existence of homosexuality and gender variation across human cultures and eras.

I learned a great deal from this book. It’s a book that every politician and judicial officer should read.

Paganini was an extraordinary violinist because of his exceptionally flexible thumb. Why was his thumb so “bendy”? Genetics. His genes provided an opportunity, and he learned how to exploit it.

Each of us is genetically unique. Our challenge is to understand our genes, which can be positive or negative. The Violinist’s Thumb is a nice introduction to the importance of DNA and the impact of genes in history. Inbreeding in the European royals led to hemophilia and ultimately contributed to the fall of the Czar and the Russian Empire. Genes have played a major role in history, art, and science.

It is a fun book with a novel perspective. 

The book is surprising not only because of the very strong amount of scientific data compiled showing that in terms of health and also various other traits, women do indeed often outperform men but also because it shows that many of the discoveries related to those scientific data were actually done by women, contrary to the false or at least biased stories we often read about, in the literature.

One of the strengths of the book is precisely how it talks about these untold stories in science and how it connects them to the main topic being discussed. I have this book assigned to my undergraduate biology course at Howard University.