Fans pick 100 books like Great and Desperate Cures

By Elliot S Valenstein,

Here are 100 books that Great and Desperate Cures fans have personally recommended if you like Great and Desperate Cures. Shepherd is a community of 12,000+ authors and super readers sharing their favorite books with the world.

When you buy books, we may earn a commission that helps keep our lights on (or join the rebellion as a member).

Book cover of An Anthropologist on Mars: Seven Paradoxical Tales

John E. Dowling Author Of Understanding the Brain: From Cells to Behavior to Cognition

From my list on healthy and compromised brains.

Why am I passionate about this?

I began research as an undergraduate at Harvard College, initially studying the effects of vitamin A deficiency on the photoreceptors in the eye that capture the light and initiate vision. After receiving my PhD and starting my own laboratory, I became fascinated with the other four classes of cells/neurons found in the retina, which begin the analysis of visual information: two being in the outer retina and two in the inner retina. We mapped out the synaptic interactions among the neurons, recorded from them, and began to put together the neural circuitries that underlie the visual messages that are sent to other parts of the brain. 

John's book list on healthy and compromised brains

John E. Dowling Why did John love this book?

One of Oliver Sack’s delightful books containing stories of individuals with various neurological disorders. I read the first one, The Man Who Mistook His Wife for a Hat, back in the 1980s  when it first came out and was hooked, now having read almost all of them.

The one I am recommending is, I believe, more relevant to an understanding of brain mechanisms. One criticism I have had of Sack’s books is that there is little in the way of neurobiological explanations for the conditions described. In my book, most chapters begin with a Sack-like story about a specific neurological condition that is then explained, as far as possible, neurobiologically in the chapter.

By Oliver Sacks,

Why should I read it?

4 authors picked An Anthropologist on Mars as one of their favorite books, and they share why you should read it.

What is this book about?

As with his previous bestseller, The Man Who Mistook His Wife for a Hat, in An Anthropologist on Mars Oliver Sacks uses case studies to illustrate the myriad ways in which neurological conditions can affect our sense of self, our experience of the world, and how we relate to those around us.

Writing with his trademark blend of scientific rigour and human compassion, he describes patients such as the colour-blind painter or the surgeon with compulsive tics that disappear in the operating theatre; patients for whom disorientation and alienation - but also adaptation - are inescapable facts of life.

'An…


Book cover of Flowers For Algernon

John E. Dowling Author Of Understanding the Brain: From Cells to Behavior to Cognition

From my list on healthy and compromised brains.

Why am I passionate about this?

I began research as an undergraduate at Harvard College, initially studying the effects of vitamin A deficiency on the photoreceptors in the eye that capture the light and initiate vision. After receiving my PhD and starting my own laboratory, I became fascinated with the other four classes of cells/neurons found in the retina, which begin the analysis of visual information: two being in the outer retina and two in the inner retina. We mapped out the synaptic interactions among the neurons, recorded from them, and began to put together the neural circuitries that underlie the visual messages that are sent to other parts of the brain. 

John's book list on healthy and compromised brains

John E. Dowling Why did John love this book?

Although this book has been around for a very long time, I only encountered it earlier this year.

It is a scientific fiction novel based on a supposed treatment given to a mentally handicapped young man (Charlie) that gave him great intelligence. This treatment had been tried earlier on mice (one being Algernon), enabling them to do cognitive tasks impossible for ordinary mice. The basis for much of the book was that the treatment was not permanent, and first, Algernon and then Charlie deteriorated back to where they were cognitively before the treatment.

The book beautifully describes what it was like (in Charlie’s own words) to be cognitively disabled before the treatment and how he was treated by people; then, when the treatment was effective, and finally, as he was deteriorating, which he recognized was happening. Although fictional, the descriptions of the cognitive changes in Charlie are compelling.

By Daniel Keyes,

Why should I read it?

15 authors picked Flowers For Algernon as one of their favorite books, and they share why you should read it. This book is for kids age 14, 15, 16, and 17.

What is this book about?

Charlie Gordon, a retarded adult, undergoes a brain operation which dramatically increases his intelligence.

Charlie becomes a genius. But can he cope emotionally? Can he develop relationships?

And how do the psychiatrists and psychologists view Charlie-as a man or as the subject of an experiment like the mouse Algernon?


Book cover of The Disordered Mind: What Unusual Brains Tell Us about Ourselves

John E. Dowling Author Of Understanding the Brain: From Cells to Behavior to Cognition

From my list on healthy and compromised brains.

Why am I passionate about this?

I began research as an undergraduate at Harvard College, initially studying the effects of vitamin A deficiency on the photoreceptors in the eye that capture the light and initiate vision. After receiving my PhD and starting my own laboratory, I became fascinated with the other four classes of cells/neurons found in the retina, which begin the analysis of visual information: two being in the outer retina and two in the inner retina. We mapped out the synaptic interactions among the neurons, recorded from them, and began to put together the neural circuitries that underlie the visual messages that are sent to other parts of the brain. 

John's book list on healthy and compromised brains

John E. Dowling Why did John love this book?

One of the world’s best neuroscientists, who won the Nobel Prize in 2000, engagingly describes neurological and cognitive diseases/conditions and how they can be debilitating but, in some cases, can lead to extraordinary mental abilities in memory, visual arts, etc.

It came out the same year as my book, and it adds to and complements it. I found the descriptions of brain disorders compelling and the history of psychiatry woven into the chapters fascinating. The relationship between certain cognitive disorders and highly creative people is discussed, and an intriguing reason for this is proposed.

By Eric R Kandel,

Why should I read it?

1 author picked The Disordered Mind as one of their favorite books, and they share why you should read it.

What is this book about?

Neurological and psychiatric disorders have long been regarded as fundamentally different, depending on whether they appear to affect the brain or the mind. In reality, the brain and the mind are inseparable. Both types of disorder can affect every aspect of brain function: from perception, action, memory and emotion to empathy, social interaction, attention and consciousness.

It is easy to view brain disorders as simply tragic or frightening. However, studying where these functions go wrong provides a window on the workings of the healthy brain, and makes it more likely that scientists and clinicians will be able to develop effective…


Book cover of Recollections of My Life

John E. Dowling Author Of Understanding the Brain: From Cells to Behavior to Cognition

From my list on healthy and compromised brains.

Why am I passionate about this?

I began research as an undergraduate at Harvard College, initially studying the effects of vitamin A deficiency on the photoreceptors in the eye that capture the light and initiate vision. After receiving my PhD and starting my own laboratory, I became fascinated with the other four classes of cells/neurons found in the retina, which begin the analysis of visual information: two being in the outer retina and two in the inner retina. We mapped out the synaptic interactions among the neurons, recorded from them, and began to put together the neural circuitries that underlie the visual messages that are sent to other parts of the brain. 

John's book list on healthy and compromised brains

John E. Dowling Why did John love this book?

I very much enjoy reading biographies and autobiographies about scientists. My favorite is Cajal’s autobiography.

Cajal is considered by many to be the Father of Neuroscience. He grew up in Spain, where he lived his entire life. He loved to draw and wanted to become an artist, but his father discouraged this, so he went to medical school. He used his artistic skills to great advantage when he began to study the brain and its cells. His drawings are meticulous, exceptionally accurate, and have never been surpassed.

Virtually every book on neuroscience includes some of his drawings. This book recounts not only his scientific career but also other of his fascinations. He loved chess and played it with individuals all over the world, but he gave it up because it was taking up too much of his time.

By Santiago Ramon y Cajal, E. Horne Craigie (translator), Juan Cano (translator)

Why should I read it?

1 author picked Recollections of My Life as one of their favorite books, and they share why you should read it.

What is this book about?

Santiago Ramón y Cajal (1852-1934) made prolific and lasting contributions to understanding "the life of the infinitely small."

Santiago Ramón y Cajal (1852-1934) made prolific and lasting contributions to understanding "the life of the infinitely small." Widely thought of as the founder of neuroscience, Cajal made remarkable explorations into the organization and function of the nervous system. His work is still referred to more than that of any other scientist in the field.W. Maxwell Cowan's foreword to this edition conveys the excitement and energy of Cajal's life and endeavors, the liveliness and flamboyance of his engagements with the microscope. Cowan…


Book cover of The Tale of the Dueling Neurosurgeons: The History of the Human Brain as Revealed by True Stories of Trauma, Madness, and Recovery

Marc Dingman Author Of Bizarre: The Most Peculiar Cases of Human Behavior and What They Tell Us about How the Brain Works

From my list on learning about your brain.

Why am I passionate about this?

My fascination with the brain began when I was an undergraduate, and since has grown into an insatiable curiosity about all things neuroscience. Today my main job is teaching courses in the health sciences at The Pennsylvania State University, but I spend much of my free time trying to find ways to make neuroscience understandable to those who share my enthusiasm for learning about it. I mostly do this through my books and a series of short neuroscience videos on my YouTube channel: Neuroscientifically Challenged.

Marc's book list on learning about your brain

Marc Dingman Why did Marc love this book?

The Tale of the Dueling Neurosurgeons is a fun, engaging, and well-written introduction to your brain and some of the most interesting characters in the history of neuroscience.

Sam Kean is an excellent science writer—the type who draws you in so much with his storytelling that you forget you’re actually learning something. By the end of this book, you’ll know more about how the brain works, but perhaps better yet you’ll have enjoyed an array of colorful historical tales that explain how our knowledge of the brain has advanced over the years.

By Sam Kean,

Why should I read it?

1 author picked The Tale of the Dueling Neurosurgeons as one of their favorite books, and they share why you should read it.

What is this book about?

For centuries, scientists had only one way to study the brain: wait for misfortune to strike - strokes, seizures, infections, lobotomies, horrendous accidents, phantom limbs, Siamese twins - and see how the victims changed afterwards. In many cases their survival was miraculous, and observers marvelled at the transformations that took place when different parts of the brain were destroyed. Parents suddenly couldn't recognise their children. Pillars of the community became pathological liars and paedophiles. Some people couldn't speak but could still sing. Others couldn't read but could write.
The stories of these people laid the foundations of modern neuroscience and,…


Book cover of The Lobotomist's Wife

Heather Frimmer Author Of Better to Trust

From my list on brain dysfunction.

Why am I passionate about this?

I am a radiologist specializing in emergency room and breast imaging and a lifelong book nerd. Though I chose radiology as my medical specialty, I have always been fascinated by the complicated workings of the human mind. I majored in psychology in college and strongly considered careers in both psychiatry and neurology. Books exploring the fragility and fallibility of the human brain never fail to catch my attention. These stories explore the essence of what it means to be human and highlight the resilience of the human spirit.  

Heather's book list on brain dysfunction

Heather Frimmer Why did Heather love this book?

There is nothing more satisfying than a well-researched story about the history of medicine. 

This shocking story takes place in the mid-twentieth century and centers on Ruth, a hospital administrator whose husband invented the ice pick lobotomy for the treatment of psychiatric illness. As the surgery gains popularity, Ruth soon learns of debilitating complications from the procedure. Could the touted miracle cure be doing more harm than good?

By Samantha Greene Woodruff,

Why should I read it?

1 author picked The Lobotomist's Wife as one of their favorite books, and they share why you should read it.

What is this book about?

An enthralling historical novel of a compassionate and relentless woman, a cutting-edge breakthrough in psychiatry, and a nightmare in the making.

Since her brother took his life after WWI, Ruth Emeraldine has had one goal: to help those suffering from mental illness. Then she falls in love with charismatic Robert Apter-a brilliant doctor championing a radical new treatment, the lobotomy. Ruth believes in it as a miracle treatment and in Robert as its genius pioneer. But as her husband spirals into deluded megalomania, Ruth can't ignore her growing suspicions. Robert is operating on patients recklessly, often with horrific results. And…


Book cover of Expect Delays: How to Reclaim Your Life, Light and Soul After Trauma

Shari Botwin Author Of Stolen Childhoods: Thriving After Abuse

From my list on healing after surviving past abuse experiences.

Why am I passionate about this?

I am a childhood abuse survivor, author, and therapist, and I am always looking for books to help me better understand the crazy healing process. I have done over two decades of therapy and have been working with clients for over twenty-eight years. In addition, I serve as an expert witness on behalf of plaintiffs who have experienced different types of trauma. Educating myself and getting the perspective from other clinicians and experts has helped me be a better therapist and expedited my therapy process!

Shari's book list on healing after surviving past abuse experiences

Shari Botwin Why did Shari love this book?

This book, by Danielle Delaney, PhD.  (10-10-10 Publishing, February 2017) is written by a survivor that I connected to after I went public about surviving childhood abuse.

It is a beautifully written book and offers the reader hope in the aftermath of living through horrific abuse experiences as a teenager. Delaney affirms the enormous amount of work and time it takes to recover from traumas like kidnapping and sexual assault. 

By Danielle Delaney,

Why should I read it?

1 author picked Expect Delays as one of their favorite books, and they share why you should read it.

What is this book about?

UNVEIL AN ESSENTIAL & UNIQUE PERSPECTIVE ABOUT HEALING FROM DEEP TRAUMA

You CAN heal ENTIRELY from severe, deep trauma - without needing a lobotomy. Through her first book, Expect Delays, Dr. Danielle Delaney shares with you the traumatic experiences of her assaults, and her journey of recovery and growth into the powerful woman and trauma expert that she is today. Recovery is not a simple path, and you will encounter detours and delays along the winding road. You will discover and uncover knowledge from the first chapter, Demolition, when an unexpected and terror-inducing life event totals you, to the final…


Book cover of How the Brain Lost Its Mind: Sex, Hysteria, and the Riddle of Mental Illness

Alberto Espay Author Of Brain Fables: The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them

From my list on rethinking brain aging and neurodegeneration.

Why am I passionate about this?

I am a professor of neurology at the University of Cincinnati, interested in the many ways in which we acquire impairments in movements, in cognition, or in both. I have sought to measure these behaviors, quantify their responses to different pharmacological treatments, and determine how they inform the biology of the aging brain. In publications along the way, I have increasingly questioned how we classify neurological diseases and treat those affected.

Alberto's book list on rethinking brain aging and neurodegeneration

Alberto Espay Why did Alberto love this book?

This book offers a captivating tale of how the increasing knowledge of one disease, syphilis, created the foundations to understanding that the brain and mind are one and the same. The authors narrate the stories of patients whose “hysteria” (today referred to as functional neurological disorder) were traced to degenerative brain lesions that only belatedly were understood to be complications caused by remote infections with the bacterium Treponema pallidum. Several chapters follow the story of the important characters depicted by André Brouillet in the Une leçon clinique à la Salpêtrière (A Clinical Lesson at the Salpêtrière), one of the most recognized paintings by neurologists, as it depicts Jean-Martin Charcot, shown among many of his disciples, demonstrating a “hysteric” seizure in one of his patients. The authors illustrate how we have gotten away with conceptualizing behaviors without biological basis and put the reader on notice that “mental illnesses” are neurological problems…

By Allan H. Ropper, Brian Burrell,

Why should I read it?

1 author picked How the Brain Lost Its Mind as one of their favorite books, and they share why you should read it.

What is this book about?

'Hugely entertaining' Guardian

'Fascinating' Mail on Sunday

In 1882, Jean-Martin Charcot was the premiere physician in Paris, having just established a neurology clinic at the infamous Salpetriere Hospital, a place that was called a 'grand asylum of human misery'. Assessing the dismal conditions, he quickly upgraded the facilities, and in doing so, revolutionized the treatment of mental illness.

Many of Charcot's patients had neurosyphilis (the advanced form of syphilis), a disease of mad poets, novelists, painters, and musicians, and a driving force behind the overflow of patients in Europe's asylums. A sexually transmitted disease, it is known as 'the great…


Book cover of Change Your Brain, Change Your Life: The Breakthrough Program for Conquering Anxiety, Depression, Obsessiveness, Lack of Focus, Anger, and Memory Problems

Kevin Hines Author Of The Art of Being Broken: How Storytelling Saves Lives

From my list on finding hope when battling with your mental health.

Why am I passionate about this?

I am immersed in the topic of brain and mental health every single day. I love devouring books on the topic because it helps me personally with my diagnosed bipolar depression. I know what it’s like to attempt suicide and to live with chronic thoughts that can be overwhelming. So, reading books like these helps me better balance my brain health, and they help me offer hope to others to whom I can recommend these kinds of books. As host of the Hinesights Podcast, where I interview folks in the field of mental health from all walks of life, being able to put a list like this together is a gift. 

Kevin's book list on finding hope when battling with your mental health

Kevin Hines Why did Kevin love this book?

I truly loved this book because Dr. Daniel Amen is the best in his class. He is a dedicated brain scientist, author, and life changer. I’ve read all of his books because they teach us all how to benefit our brains to change our lives forever.

This book has helped me personally, and so has his research. He's a personal friend and one hell of a game-changer when it comes to recognizing the importance of altering the conversation from mental health to brain health.

He is an important figure of this or any time; the world is lucky he's here to make us all better, one brain at a time. 

By Daniel G. Amen,

Why should I read it?

1 author picked Change Your Brain, Change Your Life as one of their favorite books, and they share why you should read it.

What is this book about?

NEW YORK TIMES BESTSELLER • In this completely revised and updated edition, neuropsychiatrist Dr. Daniel Amen includes effective "brain prescriptions" that can help heal your brain and change your life.

“Perfection in combining leading-edge brain science technology with a proven, user-friendly, definitive, and actionable road map to safeguard and enhance brain health and functionality.”—David Perlmutter, M.D., New York Times bestselling author of Grain Brain
 
In Change Your Brain, Change Your Life, renowned neuropsychiatrist Daniel Amen, M.D., includes new, cutting-edge research gleaned from more than 100,000 SPECT brain scans over the last quarter century and scientific evidence that your anxiety, depression,…


Book cover of Innate: How the Wiring of Our Brains Shapes Who We Are

Mark Humphries Author Of The Spike: An Epic Journey Through the Brain in 2.1 Seconds

From my list on how brains actually work.

Why am I passionate about this?

I’m a British neuroscientist and writer who’s been using computers to study the brain since 1998, and writing about it since 2016. How I ended up a neuroscientist is hard to explain, for my formative years were spent devouring science books that were not about the brain. That’s partly because finding worthwhile books about the brain is so hard – few delve into how the brain actually works, into the kinds of meaty details that, for example, Hawking offered us on physics and Dawkins on evolution. So I wrote one to solve that problem; and the books on my list are just that too: deep, insightful works on how the brain does what it does.

Mark's book list on how brains actually work

Mark Humphries Why did Mark love this book?

We neuroscientists know a lot about how brains are, but not how they come to be. This book fills that huge hole: it explains how genetics and development shape the growing brain, and the consequences this has for our personalities and our mental disorders. Mitchell’s thesis is that the stochastic nature of development is key to understanding much of the variation between brains, and it has changed the way I think about the wiring of brains.

By Kevin J. Mitchell,

Why should I read it?

1 author picked Innate as one of their favorite books, and they share why you should read it.

What is this book about?

A leading neuroscientist explains why your personal traits are more innate than you think

What makes you the way you are-and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive…


Book cover of An Anthropologist on Mars: Seven Paradoxical Tales
Book cover of Flowers For Algernon
Book cover of The Disordered Mind: What Unusual Brains Tell Us about Ourselves

Share your top 3 reads of 2024!

And get a beautiful page showing off your 3 favorite reads.

1,609

readers submitted
so far, will you?

5 book lists we think you will like!

Interested in the brain, mental disorders, and JFK?

The Brain 170 books
Mental Disorders 182 books
JFK 71 books