99 books like Upgrade

By Blake Crouch,

Here are 99 books that Upgrade fans have personally recommended if you like Upgrade. Shepherd is a community of 12,000+ authors and super readers sharing their favorite books with the world.

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Book cover of Oryx and Crake

F. D. Lee Author Of In The Slip

From my list on apocalyptic Sci-Fi novels with complex characters.

Why am I passionate about this?

I have always been fascinated with morally grey or complex characters. For me, the sign of a great novel is one where you find yourself talking about the characters as if they were real people you know. I want to experience something when I read, and characters that are flawed, imperfect, or morally grey have always intrigued me because they can take me to places I haven’t (or wouldn’t!) go myself. And, of course, they provide ample grounds for fun discussions with my friends! Sci-fi apocalyptic fiction is fertile ground for such characters, so I’ve tried to pick books you may not have heard of. I hope you like them!

F. D.'s book list on apocalyptic Sci-Fi novels with complex characters

F. D. Lee Why did F. D. love this book?

This was a book club choice, and as soon as I finished it, I bought the other two books in the trilogy. I literally couldn’t put them down! Another post-apocalypse for this list, this time, the story is told through the memories of Jimmy/Snowman. But make no mistake, the novel is about Crake, a brilliant, lonely, and terrifying young man.

As Jimmy tries to recover his past, shadowed by the gentle, green-skinned ‘children of Crake,’ he recalls the events leading up to the end of humanity. This is very much a mystery, so I must be careful what I reveal, but if you are all about misguided genius and hubris, you will adore this novel. Needless to say, with an author like Atwood, the writing is superb. 

By Margaret Atwood,

Why should I read it?

12 authors picked Oryx and Crake as one of their favorite books, and they share why you should read it.

What is this book about?

By the author of THE HANDMAID'S TALE and ALIAS GRACE

*

Pigs might not fly but they are strangely altered. So, for that matter, are wolves and racoons. A man, once named Jimmy, lives in a tree, wrapped in old bedsheets, now calls himself Snowman. The voice of Oryx, the woman he loved, teasingly haunts him. And the green-eyed Children of Crake are, for some reason, his responsibility.

*

Praise for Oryx and Crake:

'In Jimmy, Atwood has created a great character: a tragic-comic artist of the future, part buffoon, part Orpheus. An adman who's a sad man; a jealous…


Book cover of The Ferryman

Monica Chase Author Of Broken Code: The Genesis of Rebellion

From my list on Sci-fi thrillers that unravel humanity’s secrets.

Why am I passionate about this?

I’ve always been fascinated by the razor-thin line between innovation and disaster—where progress often conceals a darker potential. As a Gen-Xer who grew up questioning authority, speculative fiction became my outlet for exploring these precarious themes. Now, as an author, I channel that curiosity into stories that push the boundaries of ethical ambition, forcing us to confront the unsettling truths behind our technological dreams. This list reflects my deep love for sci-fi thrillers that don’t just entertain but challenge us to examine the hidden costs of our relentless pursuit of progress.

Monica's book list on Sci-fi thrillers that unravel humanity’s secrets

Monica Chase Why did Monica love this book?

This book didn’t just fascinate me; it shattered my understanding of utopia. Cronin’s Prospera seemed idyllic, but as I read, a gnawing unease grew. Like the protagonist, Proctor, I found myself grappling with the realization that perfection might come at a devastating cost.

The unraveling of Prospera’s facade forced me to reflect on the illusions we cling to in our own society. Cronin’s exploration of memory, loss, and the price of paradise stuck with me, making me ponder the lies we tell ourselves.

By Justin Cronin,

Why should I read it?

3 authors picked The Ferryman as one of their favorite books, and they share why you should read it.

What is this book about?

NEW YORK TIMES BESTSELLER • “Next to impossible to put down . . . exciting, mysterious, and totally satisfying.”—STEPHEN KING
 
From the New York Times bestselling author of The Passage comes a riveting standalone novel about a group of survivors on a hidden island utopia—where the truth isn't what it seems.

Founded by the mysterious genius known as the Designer, the archipelago of Prospera lies hidden from the horrors of a deteriorating outside world. In this island paradise, Prospera’s lucky citizens enjoy long, fulfilling lives until the monitors embedded in their forearms, meant to measure their physical health and psychological…


Book cover of The Atlantis Gene

Monica Chase Author Of Broken Code: The Genesis of Rebellion

From my list on Sci-fi thrillers that unravel humanity’s secrets.

Why am I passionate about this?

I’ve always been fascinated by the razor-thin line between innovation and disaster—where progress often conceals a darker potential. As a Gen-Xer who grew up questioning authority, speculative fiction became my outlet for exploring these precarious themes. Now, as an author, I channel that curiosity into stories that push the boundaries of ethical ambition, forcing us to confront the unsettling truths behind our technological dreams. This list reflects my deep love for sci-fi thrillers that don’t just entertain but challenge us to examine the hidden costs of our relentless pursuit of progress.

Monica's book list on Sci-fi thrillers that unravel humanity’s secrets

Monica Chase Why did Monica love this book?

This book blindsided me with its explosive blend of ancient mysteries and cutting-edge science. I was captivated by how Riddle wove together seemingly disparate elements—a structure in Antarctica, autism research in Jakarta—into a thrilling quest that challenges everything I thought I knew about human origins.

The ethical implications of these discoveries drove me to research and question long-held beliefs. This thriller didn’t just keep me up all night reading; it left me eager for the sequel.

By A.G. Riddle,

Why should I read it?

2 authors picked The Atlantis Gene as one of their favorite books, and they share why you should read it.

What is this book about?

THE BATTLE TO SAVE HUMANITY HAS BEGUN.

Off the coast of Antarctica, a research vessel discovers a mysterious structure buried deep within an iceberg. Entombed for thousands of years, it can't possibly be man-made. But a secretive and ruthless cabal think they know what it is... and what it means.

The Immari have spent millennia preparing for the return of humanity's ancient enemy. Faced with an extinction-level threat, they believe mankind's only chance of survival will mean sacrificing 99.9% of the planet's population. It's a price the Immari are prepared to pay.

Geneticist Kate Warner and intelligence agent David Vale…


Broken Mirror

By Cody Sisco,

Book cover of Broken Mirror

Cody Sisco Author Of Broken Mirror

New book alert!

Why am I passionate about this?

Author

Cody's 3 favorite reads in 2024

What is my book about?

A fractured mind or a global conspiracy? Uncovering the truth can be hell when nobody believes you… and you can’t even trust yourself. 

"A fantastic science fiction thriller with a sincere and important message.”—Kirkus Reviews. 

“A breathtaking, deeply dark alternate-history Earth with complex characters, layered worldbuilding, and twist after twist after twist.”—Julianna Caro, Reedsy Discovery.

Broken Mirror is the first volume in a queer psychological science fiction saga that looks at the stigma of mental illness and the hellish distrust and alienation that goes with it.

Broken Mirror

By Cody Sisco,

What is this book about?

Broken Mirror: the start of a smart, complex, and imaginative cyberpunk alternate history saga. Literary science fiction from a fresh, young voice.

In a skewed mirror universe, a mentally ill young man searches for his grandfather’s killer.

Someone killed Jefferson Eastmore. His grandson Victor is sure of it, but no one believes him.

Diagnosed with mirror resonance syndrome and shunned by Semiautonomous California society, Victor suffers from hyperempathy, blank outs, and sensory overload. Jefferson devoted his life to researching mental illness and curing Broken Mirrors like Victor through genetic engineering, but now that he’s gone, Victor must walk a narrow…


Book cover of The Breakthrough Effect

Monica Chase Author Of Broken Code: The Genesis of Rebellion

From my list on Sci-fi thrillers that unravel humanity’s secrets.

Why am I passionate about this?

I’ve always been fascinated by the razor-thin line between innovation and disaster—where progress often conceals a darker potential. As a Gen-Xer who grew up questioning authority, speculative fiction became my outlet for exploring these precarious themes. Now, as an author, I channel that curiosity into stories that push the boundaries of ethical ambition, forcing us to confront the unsettling truths behind our technological dreams. This list reflects my deep love for sci-fi thrillers that don’t just entertain but challenge us to examine the hidden costs of our relentless pursuit of progress.

Monica's book list on Sci-fi thrillers that unravel humanity’s secrets

Monica Chase Why did Monica love this book?

This book hijacked my nights and rewired my thinking about our technological future. As a tech enthusiast, I was fascinated by Liam Dunne’s supercomputer-augmented mind. But it was Oliver Scott’s terrifying genius that truly got under my skin.

The ethical dilemmas sparked heated debates with friends, and the narrative had me oscillating between awe and dread. This thriller is a rare blend of entertainment and deep questioning—a literary rollercoaster that kept me thinking long after the last page.

By Douglas E. Richards,

Why should I read it?

1 author picked The Breakthrough Effect as one of their favorite books, and they share why you should read it.

What is this book about?

A power-mad genius with the ultimate secret. Can anyone stop him? The gripping thriller by the author whose books have sold over three million copies.

“Brilliant.” “A masterpiece.” “Transcendent.” “Mind-bending.” “A must read.” “Riveting.” "The best ending I've ever read." "Amazing, remarkable, enthralling, and enlightening." "Action packed and filled with stunning surprises."

Oliver Scott is the reclusive genius behind countless world-changing breakthroughs. But how does he innovate at such a furious pace? And while most hail him as a savior, what if he’s actually the most dangerous tyrant humanity has ever seen? A man who will stop at nothing to…


Book cover of Biotechnology for Beginners

Vitaly Citovsky Author Of Agrobacterium: From Biology to Biotechnology

From my list on understand GMO plants and they are not scary.

Why am I passionate about this?

As a child, I spent all my summers in a rural environment outside the metropolitan area. This "immersion" in nature shaped my interests and hobbies, centering them on different aspects of watching and understanding life. Expectedly therefore, my formal education also focused on biology, biochemistry, and cell biology. Being a scientist is not just a profession; it is a calling, a profession, and a hobby. Biology books—strictly dry and professional and more engaging and emotional—represent an inherent aspect of a scientist's life and place his/her research in a wide context of human society. This list includes several such books which I would like to share with you.

Vitaly's book list on understand GMO plants and they are not scary

Vitaly Citovsky Why did Vitaly love this book?

This book expands my initial interest in GMO plants to other, very diverse fields of biotechnology. I find it useful and revealing for a wide spectrum of readers, from professionals to students to general readers, seeking to understand the general principles and approaches that underlie biotechnological developments that affect our lives, from plant and animal GMOs to vaccines.

By Reinhard Renneberg,

Why should I read it?

1 author picked Biotechnology for Beginners as one of their favorite books, and they share why you should read it.

What is this book about?

Biotechnology for Beginners, Third Edition presents the latest developments in the evolving field of biotechnology which has grown to such an extent over the past few years that increasing numbers of professional's work in areas that are directly impacted by the science. This book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy and animal science. This book will also appeals to lay readers who do not have a scientific background but are interested in an entertaining and informative introduction to the key aspects…


Book cover of A Crack In Creation: Gene Editing and the Unthinkable Power to Control Evolution

Kevin Davies Author Of Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing

From my list on CRISPR and genome editing.

Why am I passionate about this?

I’m a British science editor and author of a string of books on the scientific, medical, and social implications of advances in genetics research. I trained as a geneticist but found more personal satisfaction wielding a pen rather than a pipette. I’m especially drawn to science stories that have medical implications for the public and a strong narrative thread. Prior to writing Editing Humanity, I covered the race for the BRCA1 breast cancer gene (Breakthrough), the Human Genome Project (Cracking the Genome), and the rise of personal genomics (The $1,000 Genome). I’m currently writing a biography of sickle cell disease, arguably the most famous genetic mutation in human history.

Kevin's book list on CRISPR and genome editing

Kevin Davies Why did Kevin love this book?

A Crack in Creation was the first mainstream book that conveyed the extraordinary potential and ethical peril of the new genome editing technology, CRISPR. And who better to write it than the scientist who co-developed the “genetic scissors”, Professor Jennifer Doudna (who won the Nobel Prize three years later).

The book is also notable for the candid manner in which Doudna discusses her own nightmares about the potential misuse of CRISPR – fears that erupted one year later in the ‘CRISPR babies’ scandal.

By Jennifer A. Doudna, Samuel H. Sternberg,

Why should I read it?

3 authors picked A Crack In Creation as one of their favorite books, and they share why you should read it.

What is this book about?

BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY  |  Finalist for the Los Angeles Times Book Prize
  
“A powerful mix of science and ethics . . . This book is required reading for every concerned citizen—the material it covers should be discussed in schools, colleges, and universities throughout the country.”— New York Review of Books 
 
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new…


Book cover of Genentech: The Beginnings of Biotech

K. Lee Lerner Author Of Biotechnology: In Context

From my list on biotechnology.

Why am I passionate about this?

K. Lee Lerner is an author, editor, and producer of science and factual media, including four editions of the Gale Encyclopedia of Science and the Encyclopedia of Espionage, Intelligence, and Security. His expansive writing on science, climate change, disasters, disease, and global issues has earned multiple book and media awards, including books named Outstanding Academic Titles. An aviator, sailor, and member of the National Press Club in Washington, his two global circumnavigations and portfolio of work in challenging and dangerous environments reveal a visceral drive to explore and investigate. With a public intellectual's broad palate and a scientist's regard for evidence-based analysis, Lerner dissects and accessibly explains complex issues. 

K.'s book list on biotechnology

K. Lee Lerner Why did K. love this book?

Sally Smith Hughes' highly readable tale of the genesis of Genentech provides a no-holds-barred look into the gritty details of how biotech firms are born. Hughes reveals how scientists, lawyers, and venture capitalists work together and collide in a crucible of competing disciplines and desires to produce transformative advances. For those interesting in biotech entrepreneurship or simply investing in biotech, this book offers key foundational insights into the industry.

By Sally Smith Hughes,

Why should I read it?

1 author picked Genentech as one of their favorite books, and they share why you should read it.

What is this book about?

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating…


Book cover of Deal with the Devil

Michael J Brooks Author Of Republic Falling

From my list on delivering thought-provoking social inspection.

Why am I passionate about this?

Since childhood, I’ve been a consumer of fiction entertainment. I’m a fan of comic books, anime, television series, fiction books, movies, video games, etc. Influenced by all of these forms of storytelling, I seek to entertain people with my science fiction books and help take their minds off their troubles. At a young age, I also realized fiction can be a gateway into exploring and bringing awareness to crucial issues. With an MFA from Howard University, I’m naturally a creative person, and if I’m not creating, I’m not living. I hope readers will check out my latest book, and best so far, Republic Falling: Advent of a New Dawn.

Michael's book list on delivering thought-provoking social inspection

Michael J Brooks Why did Michael love this book?

What I found unique about Deal with the Devil was that it was written by two authors who specialize in writing steamy romance books, who, together, go by the pen name Kit Rocha. Genetically and cybernetically enhanced humans has always been one of my favorite sci-fi concepts. This book has two teams of enhanced humans. There is Nina and her all-female crew, who are the book’s main characters, and there is Knox and his all-male crew. I enjoyed learning about the different abilities and troubled pasts of these characters. And with the setting being in a dystopian environment, another concept I enjoy, coupled with the book having all the spiciness and sensuality you'd usually find in an urban fantasy novel, this sci-fi story was intriguing. I believe it will be a winner for adult male and female readers.

By Kit Rocha,

Why should I read it?

2 authors picked Deal with the Devil as one of their favorite books, and they share why you should read it.

What is this book about?

Deal with the Devil is Orphan Black meets the post-apocalyptic Avengers by USA Today and New York Times bestselling author duo Kit Rocha.

Nina is an information broker with a mission--she and her team of mercenary librarians use their knowledge to save the hopeless in a crumbling America.

Knox is the bitter, battle-weary captain of the Silver Devils. His squad of supersoldiers went AWOL to avoid slaughtering innocents, and now he's fighting to survive.

They're on a deadly collision course, and the passion that flares between them only makes it more dangerous. They could burn down the world, destroying each…


Book cover of Sisyphean

Marc E. Fitch Author Of Boy in the Box

From my list on brilliantly bat-shit stories.

Why am I passionate about this?

I read widely and in many genres, so coming up with a thematic list was a difficult task. However, in working on my forthcoming novel Dead Ends, in which a quiet neighborhood descends into paranoia and insanity driven by fear, politics, and technology, I sought out novels that engaged with conspiratorial thinking and violence. I admire writers who don’t hold back and fully engage with their characters and material, particularly if it means going to dark, imaginative and strange places in their work. Please keep an eye out for Dead Ends, coming from Flame Tree Press in 2023.

Marc's book list on brilliantly bat-shit stories

Marc E. Fitch Why did Marc love this book?

An absolute achievement of imagination, Torishima’s collection of novellas and novelettes is set in a future in which humans, machines, and alien life are as intertwined as the stories themselves. Attempting to sum up the various horrifying, chaotic and enigmatic worlds of this book is a fool’s errand; its breadth is staggering and can only be read to be understood. Even then, you will likely be left with more questions than answers. Sisyphean stretches itself to the breaking point and then challenges the reader to keep going, to open one’s mind to a torrid future populated by creatures who retain their humanity, but little else. Thankfully, Torishima offers his own illustrations to help you along.

By Dempow Torishima, Daniel Huddleston (translator),

Why should I read it?

1 author picked Sisyphean as one of their favorite books, and they share why you should read it.

What is this book about?

Even after the world and humanity itself have been rendered nearly unrecognizable by genetic engineering, a day in the office can feel...Sisyphean.

The company stands atop a tiny deck supported by huge iron columns a hundred meters high. The boss there is its president-a large creature of unstable, shifting form once called "human." The world of his dedicated worker contains only the deck and the sea of mud surrounding it, and and the worker's daily routine is anything but peaceful. A mosaic novel of extreme science and high weirdness, Sisyphean will change the way you see existence itself.

Japan's own…


Book cover of The Case against Perfection: Ethics in the Age of Genetic Engineering

Françoise Baylis Author Of Altered Inheritance: CRISPR and the Ethics of Human Genome Editing

From my list on genetic engineering and designer babies.

Why am I passionate about this?

I'm a philosopher with a specialization in bioethics. My work is at the intersection of policy and practice. It is grounded in a deep commitment to public education, engagement, and empowerment, as well as a strong desire to “make the powerful care.” I maintain that “the human genome belongs to us all. It’s something we have in common, and so we all have the right to have a say.” I believe the pivotal question that we all need to ask is “What kind of world do we want to live in?” Once we have an answer to this question, we can meaningfully address the more pointed question, “Will CRISPR technology help us build that world?”

Françoise's book list on genetic engineering and designer babies

Françoise Baylis Why did Françoise love this book?

Somewhat paradoxically, this treatise against genetic enhancement starts with the case of a deaf couple who want to have a deaf child.

This is a case I often discuss in exploring the difference between disease, disability, and diversity. Following on from this case description, Sandel asks, “Is it wrong to make a child deaf by design?” And what if the desired trait was not deafness but height, athletic prowess, health, or intelligence, and the aim was to gain a competitive advantage?

Would your answer be the same? In the pages that follow, Sandel builds a case against “reengineering our nature” grounded in an ethic of giftedness (i.e., a reverence for life as a gift).

He eschews the drive to mastery and insists that “[t]o appreciate children as gifts is to accept them as they come, not as objects of our design, or products of our will, or instruments of our…

By Michael J. Sandel,

Why should I read it?

1 author picked The Case against Perfection as one of their favorite books, and they share why you should read it.

What is this book about?

"Sandel explores a paramount question of our era: how to extend the power and promise of biomedical science to overcome debility without compromising our humanity. His arguments are acute and penetrating, melding sound logic with compassion."
-Jerome Groopman, author of How Doctors Think

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature-to enhance our genetic traits and those of our children. Although most people find…


5 book lists we think you will like!

Interested in genetic engineering, metamorphosis, and biotechnology?

Metamorphosis 24 books
Biotechnology 15 books