The most recommended books about medication

This is the first volume of lecture notes from the infamous Alexander (Sasha) Shulgin, “inventor” of MDMA “ecstasy or molly”. Sasha and his wife Ann are well known in the world of psychedelics for their publications based on Sasha’s incredible knowledge of chemistry, Ann’s capacity to integrate experiences, and their shared contributions to the world of psychedelia. This new book, with an introduction from Mariavittoria Mangini, is a ‘warts and all’ introduction to the chemistry of mind alteration. It is highly accessible, at times comical, and a fascinating opportunity to voyeuristically sit in on a series of Shulgin lectures that promises to pique your curiosity about our chemical lives.

I found, as a history buff, The Struggle for Drug Reform to be an eye-opener about how America’s exceptionally high drug prices among other deficits in health care quality and coverage resulted from the past exercise of power by the pharmaceutical industry, the lynchpin of America’s “medico-industrial complex.”

I was impressed by historian Tobbell’s meticulously researched account of the industry’s strategic alliances with self-interested medical scientists, not just conservative political forces, and its use of anti-communist propaganda to fight off the threat of drug pricing regulations.

I personally found important her discussions of how the industry allied with the American Medical Association against universal health care, against FDA demands for evidence about drug efficacy and safety before allowing drugs on the market, and against the threat to its profits from generic drugs. 

This account of the early years of Vertex Pharmaceuticals, from its inception as a scrappy start-up to its early work in HIV, is a must-read classic for anyone interested in how science turns into new drugs. Barry Werth’s journalistic play-by-play is a cinematic, true-to-life picture of the strategic decisions, real-world challenges, and larger-than-life personalities that underlie modern drug development. His riveting follow-up, The Antidote, continues the saga by taking readers through Vertex’s pathbreaking work to transform the care of patients with hepatitis C and cystic fibrosis.

I find Angell’s The Truth About the Drug Companies extremely valuable for teaching students about how the pharmaceutical industry translates high profits into power resources to protect and increase those profits over time.

The former New England Journal of Medicine editor exposed how drug companies enlist politicians, the FDA, and medical academia for their cause. And armies of lawyers to extend monopoly marketing rights for years.

It was my first introduction to how they spend more on marketing than research, much of that on “copy-cat” drugs of dubious superiority to ones with expired patents.

As a tax (and high drug price) payer, I was disturbed to learn how they use government funds for basic research and then rig and spin their reporting of clinical studies to inflate their products’ therapeutic value and underplay their risks. 

The improvised communities that ring the cities of Latin America have a bad reputation as squatter towns. Not so fast.

Look beyond the surface and you will see communities with strong social ties, systems of self-government, and residents who are as committed to their neighborhood as any American suburbanite. Janice Perlman has spent decades studying the Rio de Janeiro that lies behind its beaches, and gives a clear-eyed look at some of the self-built communities on the city’s edge.

Tara McGuire’s exquisite writing made me see the opioid crisis through new eyes.

Wisely, she steers clear of the brutal statistics and non-stop anguish that make many books about overdose painful to read. Instead, through a skillful blend of memoir and speculative fiction, she made me laugh, cry, and vow not to moralize. Combining journalistic research with cinematic descriptions of her son Holden’s private life, McGuire drew me into the events and decisions that led to his sudden death at 21.

Holden, like most drug users, cannot be dismissed as a self-destructive loser. Talented and vulnerable, hopeful yet flawed, he was a worthy human being. McGuire helped me understand his inner world.

I loved that it opened another culture to me in such a personal way.

Determined to escape the clutches of his sinister mafia boss, ruthless Ash Lynx stumbles across a dying man bearing a strange drug and the codename ‘Banana Fish’. As bloodshed looms over New York City, Ash meets Eiji, a gentle Japanese photographer. Together, they attempt to uncover the mystery behind Banana Fish, as danger stalks ever closer to their fledgling friendship. Dark and brutal, Banana Fish is centered on the trauma of Ash’s past as a child forced into prostitution. Handled with respect and care, the author offers Ash a chance to heal through the compassionate nature of a true friend, warding off the demons plaguing Ash’s memories. Survivors are rarely given the opportunity to be as complex and conflicted, so Ash is a character who remains of deep personal importance.

Autonomous is one of those books you finish reading and then just want to sit and stare off into space for a while.

The story takes place in a future world where Big Pharma runs basically the entire show. The main character is a drug pirate, fabricating expensive drugs to provide them to the population on the cheap… but when one of her fabbed drugs causes some horrible side effects, it kicks off a domino effect of chaos and death.

Other characters include a military agent sent to hunt our drug pirate down and his robotic, AI-powered partner. Every character is riddled with absolutely deal-breaking flaws, so if you’re looking for heroes, you’ve come to the wrong place. The story raises questions about morality, freedom, AI, and more. I can’t recommend it enough! 

The world is full of great ideas that don’t catch on. Indoor plumbing, for example, took about 2,500 years to become popular. Others, like radio, catch fire seemingly overnight. Why? Rogers produced the seminal work on this topic, which has now gone through five editions of updates.

He sets out clear patterns of how innovations get taken up—or struggle to. He delves into many examples to prove his points, and he always makes the reader think. Before you focus on your wonderful idea, think about what will make the idea be accepted quickly by the marketplace. As Rogers shows, that will save you vast amounts of work down the road.