100 books like Darwin's Plots

Richard Feynman was unique. A brilliant theoretical physicist, humorous, eccentric, and independent.

Feynman’s genius gave him a certain freedom, which he exploited to the full. The book is autobiographical and shows his often irresponsible behavior but also a relentless curiosity, and willingness to try anything, the essence of a successful scientist.

One cannot hope to imitate Feynman (and perhaps we should not: he was often mischievous, even mildly malicious); but any scientist should envy the way he approached problems in engineering as well as science—and the book is fun!

James Watson was a clever, pushy, and critical young American molecular biologist exposed to the scientific culture of Britain in the early 1950s.

The book is full of acerbic comments about “stuffy” Cambridge dons and the rules of etiquette that young Jim struggled with, all the while scheming to maintain the various fellowships that allowed him to remain in the UK and pursue his ambition: to understand the chemical nature of the genetic material, DNA.

The book provides a lively account of his collaboration with an older Brit, the brilliant Francis Crick, who was also trying to unscramble DNA. Much of the technical stuff will be incomprehensible to most, but the method the two followed is clear. The partnership was hugely fruitful and the book is a lively account of how science actually works.

Watson and Crick tried everything while coping with competitors and their criticisms as well as their… show more.

Ritchie was part of a team that attempted to replicate a famous study led by a prominent psychologist, Daryl Bem, claiming that people did better on a word memorization test if they studied the words after taking the test.

Ritchie and his co-authors attempted to replicate this study and found no evidence supporting Bem’s claim. This is but one example of a scientific crisis in that attempts to replicate influential studies published in top peer-reviewed journals fail nearly half the time. Ritchie explains and illustrates the reasons for the current replication crisis in science.

Experimental Medicine is a classic, a clear and simple account of physiological research, well-illustrated with comprehensible examples (no molecular biology needed).

It is well worth reading if only because so many of the principles that French physician Claude Bernard pioneered have been largely forgotten. Most important is his demand for certainty: “Science permits no exceptions,” an injunction now more often forgotten than obeyed. Bernard would have been appalled by, for example, a famous choice experiment in which 60% of a large group of subjects choose a less-profitable option.

The experimenters concluded that individual humans (not just groups) show risk aversion, ignoring the 40% who did not. In a similar situation, Bernard would always seek the conditions that yield a 100% result. He gives an example where he was able to resolve uncertainty concerning the sensitivity of spinal roots.

We’re still waiting for any serious effort to achieve a Bernardian certainty… show more.

Yara is a girl with a passion for science who is determined to make new discoveries. The book has educational back matter explaining the scientific method of making new discoveries and lays out each step in the process clearly that young readers can follow. It will inspire children to start experimenting on their own. Like every good scientist, Yara starts with a question, makes observations, and comes up with a hypothesis... but each time she starts an experiment, her dog, Renzo, ruins it! Yara sets a great example for young readers to pursue scientific studies. In this humorous story, there is clear evidence that scientific method works as well for dogs as for people. 

“Why most published research findings are false” was a 2005 paper that kicked off a crisis in science about failures to replicate, creating gaping cracks in the bedrock of science. Science Fictions explains this replication crisis and prescribes remedies. The book is written in an entertaining style, which led to its inclusion in the shortlist of the Royal Society Science Book Prize for 2021. Psychology is the poster child for the replication crisis. One of the things I like about genetics is that its findings consistently replicate, beginning with the fundamental finding that about half of the differences between people on psychological traits can be explained by inherited DNA differences.

A book about pharmaceutical corruption and manipulative science can rarely make me laugh out loud, but Bad Science does just that.

Not only did the book make me a better advocate for my health by teaching me what red flags to look out for in research and shady science journalism, but it kept me consistently entertained to the point where I was disappointed when the book ended. It should be required reading in all high school science classes. 

Better than the original, I daresay. This fan-fic explores an alternate world where Harry Potter, a household name amongst people of my generation, is not his classic self but rather a young genius who applies science to his wizarding powers whenever possible.

What I especially appreciate about this novel is how thoughtfully its plot was developed—while perhaps a stretch for me to call it explicitly cerebral, it certainly borders on the genre. This world’s Harry faces his challenges in such a methodical way (sometimes overly so!) that I was actively making guesses or getting surprised on an almost chapterly basis.

Your kiddo is excited about science… now what? Science experiments at home don’t have to be hard or hazardous. Chrystal Chatterton’s Awesome Science Experiments uses ordinary household products or items that are very easy to find. The instructions are step by step and simple to follow. Best of all the concepts are, well, real science. Chatterton explains the ideas in understandable but authentic scientific language—no dumbing things down here. Best of all these projects are a lot of fun!

This book has always been one of my all-time favorites because I love the clarity of Lewis’ writing and it deals with the real-world challenges faced by scientists in general and medical doctors in particular. The moral, financial, and romantic dilemmas faced by Martin Arrowsmith constantly keep my teeth on edge as I read this book, never leaving me starved for excitement or something unexpected at every turn. I love how Martin personally transforms throughout the novel and deals in various ways with the emotional challenges of different types of romantic relationships as he faces the obstacles within his career that ultimately shape his internal moral fiber.