The best books about the opioid crisis

10 authors have picked their favorite books about the opioid crisis and why they recommend each book.

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Pain Killer

By Barry Meier,

Book cover of Pain Killer: An Empire of Deceit and the Origin of America's Opioid Epidemic

Meier’s takedown of Purdue Pharma was ahead of its time. First published in 2003, Pain Killer was updated and re-published in 2018, Meier’s book is a hard-hitting account of the early causes of the opioid crisis. He shows how Purdue tried to hide information about OxyContin’s widespread abuse and the painkiller’s addictive nature. He also spotlights the Justice Department’s repeated failures to combat the drug epidemic. Meier is a former reporter at The New York Times. At one point, the Times’ editors yanked Meier off the opioid beat in response to complaints by Purdue Pharma lawyers. The complaints, of course, were unfounded, and editors later admitted they had been duped. I’m glad it didn’t stop Meier from writing and updating this landmark book.

Pain Killer

By Barry Meier,

Why should I read it?

1 author picked Pain Killer as one of their favorite books, and they share why you should read it.

What is this book about?

Soon to be a major Netflix series

Every catastrophe has a beginning. For the opioid crisis in America, the seed was a drug called OxyContin.

First hailed as a miracle drug for severe pain in the early 1990s, OxyContin went on to ignite a plague of addiction and death across America, fuelled by the aggressive marketing of its maker, Purdue Pharma and the billionaire Sackler brothers who owned the company.

Investigative journalist Barry Meier was the first to write about the elusive Sackler family, their role in this catastrophic epidemic and the army of local doctors, law enforcement and worried…


Who am I?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 


I wrote...

Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

By Eric Eyre,

Book cover of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

What is my book about?

Death In Mud Lick is a true-crime thriller about how a group of underdogs took on the Goliaths of the opioid industry. Set in West Virginia’s southern coalfields, the book chronicles Debbie Preece’s fight for justice on behalf of her brother, a coal miner who died after overdosing on OxyContin. I wanted to tell the story behind the story for families impacted by the opioid crisis; It’s a rigged system—made up of rogue doctors, pharmacists, distributors, manufacturers, lobbyists, and politicians—that raked in billions of dollars and cost hundreds of thousands of lives. At its heart, Death in Mud Lick is a story about resilience and redemption, holding the powerful accountable, and overcoming monumental odds. Sometimes, persistence pays off. Sometimes, underdogs do win.

Dreamland

By Sam Quinones,

Book cover of Dreamland: The True Tale of America's Opiate Epidemic

For years, Dreamland has been my go-to book to understand the opioid crisis. Quinones, a former reporter with The Los Angeles Times, skillfully weaves the stories of a heroin drug syndicate based in Mexico—known as the “Xalisco Boys”—and the unfettered prescribing of pain pills in the U.S. The combination battered towns and cities. His book won the National Book Critics’ Circle Award for nonfiction.    

Dreamland

By Sam Quinones,

Why should I read it?

1 author picked Dreamland as one of their favorite books, and they share why you should read it.

What is this book about?

Winner of the NBCC Award for General Nonfiction

Named on Slate's 50 Best Nonfiction Books of the Past 25 Years, Amazon's Best Books of the Year 2015--Michael Botticelli, U.S. Drug Czar (Politico) Favorite Book of the Year--Angus Deaton, Nobel Prize Economics (Bloomberg/WSJ) Best Books of 2015--Matt Bevin, Governor of Kentucky (WSJ) Books of the Year--Slate.com's 10 Best Books of 2015--Entertainment Weekly's 10 Best Books of 2015 --Buzzfeed's 19 Best Nonfiction Books of 2015--The Daily Beast's Best Big Idea Books of 2015--Seattle Times' Best Books of 2015--Boston Globe's Best Books of 2015--St. Louis Post-Dispatch's Best Books of 2015--The Guardian's The Best…


Who am I?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 


I wrote...

Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

By Eric Eyre,

Book cover of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

What is my book about?

Death In Mud Lick is a true-crime thriller about how a group of underdogs took on the Goliaths of the opioid industry. Set in West Virginia’s southern coalfields, the book chronicles Debbie Preece’s fight for justice on behalf of her brother, a coal miner who died after overdosing on OxyContin. I wanted to tell the story behind the story for families impacted by the opioid crisis; It’s a rigged system—made up of rogue doctors, pharmacists, distributors, manufacturers, lobbyists, and politicians—that raked in billions of dollars and cost hundreds of thousands of lives. At its heart, Death in Mud Lick is a story about resilience and redemption, holding the powerful accountable, and overcoming monumental odds. Sometimes, persistence pays off. Sometimes, underdogs do win.

Dopesick

By Beth Macy,

Book cover of Dopesick: Dealers, Doctors, and the Drug Company That Addicted America

Reading a book about people taking prescribed drugs end up being swallowed whole by addiction is heartbreaking. Realizing how easily kids can fall into that trap is terrifying. Knowing that much of that agony is fueled by aggressive profit-seeking is infuriating. Amidst the pain of this well-told story are heroes fighting to stop the onslaught. It reminds us that on the knife’s edge of life, it’s way too easy to fall to either side.   

Dopesick

By Beth Macy,

Why should I read it?

2 authors picked Dopesick as one of their favorite books, and they share why you should read it.

What is this book about?

Journalist Beth Macy's definitive account of America's opioid epidemic "masterfully interlaces stories of communities in crisis with dark histories of corporate greed and regulatory indifference" (New York Times) -- from the boardroom to the courtroom and into the living rooms of Americans.
In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous…


Who am I?

I’ve dedicated my life to repairing the world. This work has taken on many forms – helping low-income people grow community gardens for food and beauty, providing fuel subsidies that helped people combat frigid New England winters, and working on building affordable housing and economic development programs in rural and urban communities. Ultimately, these experiences brought me to create graduate programs where students could learn how to lead healthy nonprofit organizations. Part of their education involved learning how to pass laws based on my own successful experience. I realized then that I had a passion for providing everyday citizens with simple tools they too could use to make a difference.    


I wrote...

The Empowered Citizens Guide: 10 Steps to Passing a Law that Matters to You

By Pat Libby,

Book cover of The Empowered Citizens Guide: 10 Steps to Passing a Law that Matters to You

What is my book about?

This book is for anyone who sees a glaring injustice or community-wide problem and feels like screaming, “there ought to be law!” but doesn’t know how to make it happen. Pat Libby makes the work of conducting a successful grassroots lobbying campaign seem relatively painless by sharing her easy-to-follow formula and pulling the curtain back on things we think we should know but don’t. The book is funny, relatable, and illustrated by a real-life example of people who successfully used her strategy to pass a law. For those who are passionate about creating change in their communities, cities, or states this book provides a simple recipe for making a difference.

Empire of Pain

By Patrick Radden Keefe,

Book cover of Empire of Pain: The Secret History of the Sackler Dynasty

The New Yorker writer and author of the New York Times bestseller Say Anything—unveils the secrets and lies of the Sackler family, the billionaire owners of Purdue Pharma. Keefe is a master of narrative storytelling and an incredible researcher, and this book made me want to scream at the greed and callousness of the Sacklers. Many see the family as downright evil, and understandably so. Since Keefe’s book came out, a number of museums and organizations have tried to distance themselves from the Sacklers. Keefe also testified before a congressional committee that aimed to hold the Sacklers accountable for the opioid crisis. Keefe poured through hundreds of thousands of documents—including messages sent from one family member to another—as part of his definitive investigation of the Sacklers. I admire reporters like Keefe who are willing to do the tedious work of scouring records.

Empire of Pain

By Patrick Radden Keefe,

Why should I read it?

3 authors picked Empire of Pain as one of their favorite books, and they share why you should read it.

What is this book about?

NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing.

"A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate

The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom…


Who am I?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 


I wrote...

Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

By Eric Eyre,

Book cover of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

What is my book about?

Death In Mud Lick is a true-crime thriller about how a group of underdogs took on the Goliaths of the opioid industry. Set in West Virginia’s southern coalfields, the book chronicles Debbie Preece’s fight for justice on behalf of her brother, a coal miner who died after overdosing on OxyContin. I wanted to tell the story behind the story for families impacted by the opioid crisis; It’s a rigged system—made up of rogue doctors, pharmacists, distributors, manufacturers, lobbyists, and politicians—that raked in billions of dollars and cost hundreds of thousands of lives. At its heart, Death in Mud Lick is a story about resilience and redemption, holding the powerful accountable, and overcoming monumental odds. Sometimes, persistence pays off. Sometimes, underdogs do win.

Long Bright River

By Liz Moore,

Book cover of Long Bright River

I can’t even tell you how many times in many years working for newspapers that I rushed out after hearing a body had been found in an empty house or neglected alley. In almost every case, I would arrive to have police officers tell me, “No story here. No homicide. Just another overdose.” The newspaper didn’t tally overdose deaths as it did murders, even if many fatalities are linked to heroin that has been mixed with fentanyl without the users’ knowledge. It’s very rare for those who sell the killer substance to face homicide charges. 

The city is basically another character in this book. While the opioid epidemic had touched communities across the country, Philadelphia’s Kensington neighborhood is widely acknowledged as a disaster zone. A 2018 New York Times article called Kensington is the largest open-air narcotics market on the east coast. 

The plot centers on Philadelphia police officer Mickey…

Long Bright River

By Liz Moore,

Why should I read it?

4 authors picked Long Bright River as one of their favorite books, and they share why you should read it.

What is this book about?

ONE OF BARACK OBAMA'S FAVORITE BOOKS OF THE YEAR

NAMED A BEST BOOK OF THE YEAR BY NPR, PARADE, REAL SIMPLE, and BUZZFEED

AN INSTANT NEW YORK TIMES BESTSELLER

A GOOD MORNING AMERICA BOOK CLUB PICK

"[Moore’s] careful balance of the hard-bitten with the heartfelt is what elevates Long Bright River from entertaining page-turner to a book that makes you want to call someone you love.” – The New York Times Book Review
 
"This is police procedural and a thriller par excellence, one in which the city of Philadelphia itself is a character (think Boston and Mystic River). But it’s…


Who am I?

My usual answer, when someone asks me where I live in Philadelphia, is: “Have you seen the Rocky movies, where he’s running through that open fruit/vegetable market? I’m three blocks from there.” I’ve called Philadelphia home for more than 20 years. I’m clearly a big fan, having now written four books about the city. I include a reference to the city’s most famous fictional character in my children’s alphabet book Philadelphia A to Z. In More Philadelphia Murals and the Stories They Tell, I got to tell stories about the country’s largest public art program. In This Used To Be Philadelphia, I told the then and now stories of dozens of city locations.


I wrote...

Walking Philadelphia: 30 Walking Tours Exploring Art, Architecture, History, and Little-Known Gems

By Natalie Pompilio, Tricia Pompilio,

Book cover of Walking Philadelphia: 30 Walking Tours Exploring Art, Architecture, History, and Little-Known Gems

What is my book about?

Walking Philadelphia:30 Walking Tours Featuring Art, Architecture, History and Little-Known Gems is my first collaboration with my photographer sister, Tricia. I tried to include stories I would enjoy hearing. You’ll learn how to correctly order a cheesesteak, the many meanings of “jawn,” and some unexpected Philadelphia firsts, including the country’s first kidnapping for ransom.

For my five books, I chose works of fiction set in the City of Brotherly Love (and Sisterly Affection, as the city’s promotional materials often add.) Two of these books—As Bright as Heaven and Philadelphia Fireare linked to historic city events. Long Bright River, Such a Fun Age, and With the Fire on High touch on real-life social issues including teen pregnancy, substance abuse disorder and racial prejudice. Each story is very different. Each book deserves a read.

Why Did I Ever

By Mary Robison,

Book cover of Why Did I Ever

Why Did I Ever falls into my favorite genre of fiction, which I will describe loosely as “narrated by a sardonic, wincingly funny, tragic woman.” (See also: Lorrie Moore, Amy Hempel, Lauren Groff, Mary Gaitskill, among others.)

The narrator, Money, is a self-sabotaging script doctor whose daughter, Mev, is addicted to opioids, and whose son is under police protection following a violent assault. 

As a seemingly directionless woman who spends much of the book driving or sourcing Ritalin, Money counts, in my books, as a “transgressive” mother. She’s also charming and likable. This book is dark and deeply affecting at times. At many other times, it’s hilarious. I recommend it to anyone who loves that hinterland — between the tragic and darkly funny.

Why Did I Ever

By Mary Robison,

Why should I read it?

1 author picked Why Did I Ever as one of their favorite books, and they share why you should read it.

What is this book about?

"Tense, moving, and hilarious . . . [A] dark jewel of a novel." ―Francine Prose, O, The Oprah Magazine

Three husbands have left her. I.R.S. agents are whamming on her door. And her beloved cat has gone missing. She's back and forth between Melanie, her secluded Southern town, and L.A., where she has a weakening grasp on her job as a script doctor. Having been sacked by most of the studios and convinced that her dealings with Hollywood have fractured her personality, Money Breton talks to herself nonstop. She glues and hammers and paints every item in her place. She…


Who am I?

While it only simmers in the background of Demi-Gods, I find myself returning to this theme in my fiction — of mothers behaving badly. The topic fascinates me because we live in a society that idealizes the Mother. So much so that we have removed sex and desire from this archetype. We even made Mary, the “universal mother,” a virgin. As someone with a womb, society expects me to have children. (I don’t yet.) Fiction has provided a space for me to disentangle my own thoughts around motherhood — on what I might claim for myself, and what I absolutely refuse to take on. 


I wrote...

Demi-Gods

By Eliza Robertson,

Book cover of Demi-Gods

What is my book about?

Demi-Gods follows the story of Willa, who is growing up on an island off the west coast of Canada in the 1950s. One summer, she becomes engrossed with her step-brother, Patrick, from California. Patrick is a golden boy, clever, yet conniving — pushing 9-year-old Willa toward illicit tasks. As Willa becomes a teenager and pays a visit to California, her relationship with Patrick grows more dizzying. 

A few themes preoccupied me while I wrote this novel. For one, desire: how desire can be inconvenient and shameful, especially when we desire those who are bad for us. Second: I was interested in how we exalt each other. How we perceive those we desire as demigods or idols.

American Overdose

By Chris McGreal,

Book cover of American Overdose: The Opioid Tragedy in Three Acts

McGreal’s book fell a bit under the radar, but in my mind, it’s one of the best books of reportage on the opioid epidemic. As a reporter for The Guardian, McGreal covered the drug crisis for years. American Overdose connects all the dots that caused it. The book starts out, “Even as a teenager, Henry Vinson wanted to be an undertaker,” then takes flight from the hollows of West Virginia to the halls of Congress. McGreal is a tenacious reporter and a superb writer. He’s one of the first reporters to lay bare the Food and Drug Administration’s cozy relationship with Purdue Pharma. And he introduces readers to former DEA agent Joe Rannazzisi, who tried to put the brakes on massive shipments of painkillers to small towns across America, but was forced to step aside after Big Pharma complained about him to powerful U.S. lawmakers. The story builds from…

American Overdose

By Chris McGreal,

Why should I read it?

1 author picked American Overdose as one of their favorite books, and they share why you should read it.

What is this book about?

LONGLISTED FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2019

A devastating portrait of America's opioid painkiller epidemic - the deadliest drug crisis in US history.

One hundred and fifty Americans are killed each day by the opioid epidemic. But, as Chris McGreal reveals it was an avoidable tragedy driven by bad science, corporate greed and a corrupted medical system. He tells the stories of the families devastated by painkillers they thought would heal, and the physicians and scientists who took on the drug companies behind the epidemic. American Overdose is a powerful account of the terrible human cost of the…


Who am I?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 


I wrote...

Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

By Eric Eyre,

Book cover of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

What is my book about?

Death In Mud Lick is a true-crime thriller about how a group of underdogs took on the Goliaths of the opioid industry. Set in West Virginia’s southern coalfields, the book chronicles Debbie Preece’s fight for justice on behalf of her brother, a coal miner who died after overdosing on OxyContin. I wanted to tell the story behind the story for families impacted by the opioid crisis; It’s a rigged system—made up of rogue doctors, pharmacists, distributors, manufacturers, lobbyists, and politicians—that raked in billions of dollars and cost hundreds of thousands of lives. At its heart, Death in Mud Lick is a story about resilience and redemption, holding the powerful accountable, and overcoming monumental odds. Sometimes, persistence pays off. Sometimes, underdogs do win.

The Great American Drug Deal

By Peter Kolchinsky,

Book cover of The Great American Drug Deal: A New Prescription for Innovative and Affordable Medicines

What do we mean when we say “drug prices are too high” – and how can we fix them? In clear prose, Peter Kolchinsky, a successful biotech investor at RA Capital, clarifies the difference between list, net, and out-of-pocket drug costs, and explains how various parts of the system – drug companies, insurers, and pharmacy benefit managers (PBMs) – fit together to determine them. He also includes several detailed and timely suggestions for reform that would reduce the burden on patients and sustain biopharma innovation.

The Great American Drug Deal

By Peter Kolchinsky,

Why should I read it?

1 author picked The Great American Drug Deal as one of their favorite books, and they share why you should read it.

What is this book about?

Developing life-changing drugs is risky and expensive—but that’s not what makes them unaffordable.Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need.Do we really have to choose between affordability and innovation?In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive No. The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced…


Who am I?

Frank S. David, MD, PhD leads the biopharma consulting firm Pharmagellan, where he advises drug companies and investors on R&D and business strategy. He is also an academic researcher on strategy, regulation, and policy in the drug industry; a member of the Harvard-MIT Center for Regulatory Science; and a former blogger at Forbes.com.


I wrote...

The Pharmagellan Guide to Analyzing Biotech Clinical Trials

By Frank S. David,

Book cover of The Pharmagellan Guide to Analyzing Biotech Clinical Trials

What is my book about?

If you're a biotech executive, investor, adviser, or entrepreneur -- or aspire to be one --  you’re supposed to understand clinical trial results. But what if you’re not an expert in study design or biostatistics? The Pharmagellan Guide to Analyzing Biotech Clinical Trials will give you the foundation you need to analyze journal articles, press releases, and investor presentations about studies of new drugs with more confidence.

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