The most recommended books about the opioid crisis

Who picked these books? Meet our 11 experts.

11 authors created a book list connected to the opioid crisis, and here are their favorite opioid crisis books.
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Book cover of Holden, After and Before: Love Letter for a Son Lost to Overdose

Adriana Barton Author Of Wired for Music: A Search for Health and Joy Through the Science of Sound

From Adriana's 3 favorite reads in 2023.

Why am I passionate about this?

Author Muse chaser Science geek

Adriana's 3 favorite reads in 2023

Adriana Barton Why did Adriana love this book?

Tara McGuire’s exquisite writing made me see the opioid crisis through new eyes.

Wisely, she steers clear of the brutal statistics and non-stop anguish that make many books about overdose painful to read. Instead, through a skillful blend of memoir and speculative fiction, she made me laugh, cry, and vow not to moralize. Combining journalistic research with cinematic descriptions of her son Holden’s private life, McGuire drew me into the events and decisions that led to his sudden death at 21.

Holden, like most drug users, cannot be dismissed as a self-destructive loser. Talented and vulnerable, hopeful yet flawed, he was a worthy human being. McGuire helped me understand his inner world.

By Tara McGuire,

Why should I read it?

1 author picked Holden, After and Before as one of their favorite books, and they share why you should read it.

What is this book about?

is a moving meditation on grief: a stunning book that traces Tara McGuire’s excavation and documentation of the life path of her son Holden, a graffiti artist who died of an accidental opioid overdose at the age of twenty-one. Beginning with Holden’s death and leaping through time and space, McGuire employs fact, investigation, memory, fantasy, and even fabrication in her search for understanding not only of her son’s tragic death, but also his beautiful life. She navigates and writes across the many blank spaces to form a story of discovery and humanity, examining themes of grief, pain, mental illness, trauma,…


Book cover of The Last Exchange

Heather Day Gilbert Author Of No Filter

From Heather's 3 favorite reads in 2023.

Why am I passionate about this?

Author Viking-era aficionado Agatha Christie lover Flower gardener Video gamer

Heather's 3 favorite reads in 2023

Heather Day Gilbert Why did Heather love this book?

The Last Exchange has everything — memorable characters, a driving plotline, stunning twists, and—an extra delight for me as an author — writing that sometimes feels poetic without being pretentious.

This is the kind of storyline that makes you care. Real-world situations (like opioid addiction) are handled thoughtfully and portrayed realistically. Readers will find themselves invested in the compelling characters, rooting for their happy endings.

I've already recommended this book to a wide range of reader friends because I was so impressed with it. This was definitely a standout read of 2023 for me.

By Charles Martin,

Why should I read it?

1 author picked The Last Exchange as one of their favorite books, and they share why you should read it.

What is this book about?

"Here's the catch-even if I make it out of here alive, I need a reason to breathe again."

When MacThomas Pockets finished his last tour as part of the Scottish Special Forces, he was hired to consult for a film director to finesse some scenes that weren't working. In a twist he never saw coming, he ended up moving to L.A. to work as the bodyguard for movie star Maybe Joe Sue.

It didn't take long for Pockets to realize there were two Joe Sues: The Joe Sue the public saw with her perfect life and her Hollywood husband. And…


Book cover of Pharma: Greed, Lies, and the Poisoning of America

Mikkael A. Sekeres Author Of Drugs and the FDA: Safety, Efficacy, and the Public's Trust

From my list on the good, bad, beautiful, and ugly in medicine.

Why am I passionate about this?

As a cancer doctor, I have spent two decades dedicated to understanding the causes and therapy of cancer, how my patients experience their diagnosis and treatment, and how meaningful improvements in their experience should be reflected in the criteria we use to approve cancer drugs approval in the U.S., to improve their lives. In over 100 essays published in outlets like The New York Times and The Washington Post and in two books, I sing the stories of my patients as I learn from their undaunted spirits and their utter humanity, as I try to figure out how to be a better doctor, and a better person.

Mikkael's book list on the good, bad, beautiful, and ugly in medicine

Mikkael A. Sekeres Why did Mikkael love this book?

There’s a seedy side to the pharmaceutical industry that started well before the creation of the FDA, and continues through the modern era, fueling the epidemic of opioid drug dependency.

In Pharma, Posner’s comprehensive reporting introduces us to brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company executives often blinded by greed.

We learn how the Sacklers built a culture of pain relief on the shoulders of oxycontin – one that ultimately led to the lowest survival rates for Americans in a century.

By Gerald Posner,

Why should I read it?

1 author picked Pharma as one of their favorite books, and they share why you should read it.

What is this book about?

Award-winning journalist and New York Times bestselling author Gerald Posner traces the heroes and villains of the trillion-dollar-a-year pharmaceutical industry and uncovers how those once entrusted with improving life have often betrayed that ideal to corruption and reckless profiteering-with deadly consequences.

Pharmaceutical breakthroughs such as anti biotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on pre scription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning…


Book cover of Long Bright River

Yvonne Osborne Author Of Let Evening Come

From Yvonne's 3 favorite reads in 2024.

Why am I passionate about this?

Author Organic Gardener Environmentalist Reader Traveler Birder

Yvonne's 3 favorite reads in 2024

Yvonne Osborne Why did Yvonne love this book?

It took me into the underbelly of Philadelpia, a city I was unfamiliar with, from the pov of a female police officer.

By Liz Moore,

Why should I read it?

6 authors picked Long Bright River as one of their favorite books, and they share why you should read it.

What is this book about?

ONE OF BARACK OBAMA'S FAVORITE BOOKS OF THE YEAR

NAMED A BEST BOOK OF THE YEAR BY NPR, PARADE, REAL SIMPLE, and BUZZFEED

AN INSTANT NEW YORK TIMES BESTSELLER

A GOOD MORNING AMERICA BOOK CLUB PICK

"[Moore’s] careful balance of the hard-bitten with the heartfelt is what elevates Long Bright River from entertaining page-turner to a book that makes you want to call someone you love.” – The New York Times Book Review
 
"This is police procedural and a thriller par excellence, one in which the city of Philadelphia itself is a character (think Boston and Mystic River). But it’s…


Book cover of Why Did I Ever

Eliza Robertson Author Of Demi-Gods

From my list on featuring transgressive mothers.

Why am I passionate about this?

While it only simmers in the background of Demi-Gods, I find myself returning to this theme in my fiction — of mothers behaving badly. The topic fascinates me because we live in a society that idealizes the Mother. So much so that we have removed sex and desire from this archetype. We even made Mary, the “universal mother,” a virgin. As someone with a womb, society expects me to have children. (I don’t yet.) Fiction has provided a space for me to disentangle my own thoughts around motherhood — on what I might claim for myself, and what I absolutely refuse to take on. 

Eliza's book list on featuring transgressive mothers

Eliza Robertson Why did Eliza love this book?

Why Did I Ever falls into my favorite genre of fiction, which I will describe loosely as “narrated by a sardonic, wincingly funny, tragic woman.” (See also: Lorrie Moore, Amy Hempel, Lauren Groff, Mary Gaitskill, among others.)

The narrator, Money, is a self-sabotaging script doctor whose daughter, Mev, is addicted to opioids, and whose son is under police protection following a violent assault. 

As a seemingly directionless woman who spends much of the book driving or sourcing Ritalin, Money counts, in my books, as a “transgressive” mother. She’s also charming and likable. This book is dark and deeply affecting at times. At many other times, it’s hilarious. I recommend it to anyone who loves that hinterland — between the tragic and darkly funny.

By Mary Robison,

Why should I read it?

1 author picked Why Did I Ever as one of their favorite books, and they share why you should read it.

What is this book about?

"Tense, moving, and hilarious . . . [A] dark jewel of a novel." ―Francine Prose, O, The Oprah Magazine

Three husbands have left her. I.R.S. agents are whamming on her door. And her beloved cat has gone missing. She's back and forth between Melanie, her secluded Southern town, and L.A., where she has a weakening grasp on her job as a script doctor. Having been sacked by most of the studios and convinced that her dealings with Hollywood have fractured her personality, Money Breton talks to herself nonstop. She glues and hammers and paints every item in her place. She…


Book cover of Pain Killer: An Empire of Deceit and the Origin of America's Opioid Epidemic

Eric Eyre Author Of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

From my list on the opioid crisis written by journalists.

Why am I passionate about this?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 

Eric's book list on the opioid crisis written by journalists

Eric Eyre Why did Eric love this book?

Meier’s takedown of Purdue Pharma was ahead of its time. First published in 2003, Pain Killer was updated and re-published in 2018, Meier’s book is a hard-hitting account of the early causes of the opioid crisis. He shows how Purdue tried to hide information about OxyContin’s widespread abuse and the painkiller’s addictive nature. He also spotlights the Justice Department’s repeated failures to combat the drug epidemic. Meier is a former reporter at The New York Times. At one point, the Times’ editors yanked Meier off the opioid beat in response to complaints by Purdue Pharma lawyers. The complaints, of course, were unfounded, and editors later admitted they had been duped. I’m glad it didn’t stop Meier from writing and updating this landmark book.

By Barry Meier,

Why should I read it?

1 author picked Pain Killer as one of their favorite books, and they share why you should read it.

What is this book about?

Soon to be a major Netflix series

Every catastrophe has a beginning. For the opioid crisis in America, the seed was a drug called OxyContin.

First hailed as a miracle drug for severe pain in the early 1990s, OxyContin went on to ignite a plague of addiction and death across America, fuelled by the aggressive marketing of its maker, Purdue Pharma and the billionaire Sackler brothers who owned the company.

Investigative journalist Barry Meier was the first to write about the elusive Sackler family, their role in this catastrophic epidemic and the army of local doctors, law enforcement and worried…


Book cover of American Overdose: The Opioid Tragedy in Three Acts

Eric Eyre Author Of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

From my list on the opioid crisis written by journalists.

Why am I passionate about this?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 

Eric's book list on the opioid crisis written by journalists

Eric Eyre Why did Eric love this book?

McGreal’s book fell a bit under the radar, but in my mind, it’s one of the best books of reportage on the opioid epidemic. As a reporter for The Guardian, McGreal covered the drug crisis for years. American Overdose connects all the dots that caused it. The book starts out, “Even as a teenager, Henry Vinson wanted to be an undertaker,” then takes flight from the hollows of West Virginia to the halls of Congress. McGreal is a tenacious reporter and a superb writer. He’s one of the first reporters to lay bare the Food and Drug Administration’s cozy relationship with Purdue Pharma. And he introduces readers to former DEA agent Joe Rannazzisi, who tried to put the brakes on massive shipments of painkillers to small towns across America, but was forced to step aside after Big Pharma complained about him to powerful U.S. lawmakers. The story builds from…

By Chris McGreal,

Why should I read it?

1 author picked American Overdose as one of their favorite books, and they share why you should read it.

What is this book about?

LONGLISTED FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2019

A devastating portrait of America's opioid painkiller epidemic - the deadliest drug crisis in US history.

One hundred and fifty Americans are killed each day by the opioid epidemic. But, as Chris McGreal reveals it was an avoidable tragedy driven by bad science, corporate greed and a corrupted medical system. He tells the stories of the families devastated by painkillers they thought would heal, and the physicians and scientists who took on the drug companies behind the epidemic. American Overdose is a powerful account of the terrible human cost of the…


Book cover of Dreamland: The True Tale of America's Opiate Epidemic

Eric Eyre Author Of Death in Mud Lick: A Coal Country Fight Against the Drug Companies That Delivered the Opioid Epidemic

From my list on the opioid crisis written by journalists.

Why am I passionate about this?

I’m a West Virginia-based journalist. I have covered the opioid epidemic for nearly 10 years. In 2017, I was awarded the Pulitzer Prize for Investigative Reporting for stories about massive shipments of OxyContin and other painkillers to small towns in Appalachia. 

Eric's book list on the opioid crisis written by journalists

Eric Eyre Why did Eric love this book?

For years, Dreamland has been my go-to book to understand the opioid crisis. Quinones, a former reporter with The Los Angeles Times, skillfully weaves the stories of a heroin drug syndicate based in Mexico—known as the “Xalisco Boys”—and the unfettered prescribing of pain pills in the U.S. The combination battered towns and cities. His book won the National Book Critics’ Circle Award for nonfiction.    

By Sam Quinones,

Why should I read it?

1 author picked Dreamland as one of their favorite books, and they share why you should read it.

What is this book about?

Winner of the NBCC Award for General Nonfiction

Named on Slate's 50 Best Nonfiction Books of the Past 25 Years, Amazon's Best Books of the Year 2015--Michael Botticelli, U.S. Drug Czar (Politico) Favorite Book of the Year--Angus Deaton, Nobel Prize Economics (Bloomberg/WSJ) Best Books of 2015--Matt Bevin, Governor of Kentucky (WSJ) Books of the Year--Slate.com's 10 Best Books of 2015--Entertainment Weekly's 10 Best Books of 2015 --Buzzfeed's 19 Best Nonfiction Books of 2015--The Daily Beast's Best Big Idea Books of 2015--Seattle Times' Best Books of 2015--Boston Globe's Best Books of 2015--St. Louis Post-Dispatch's Best Books of 2015--The Guardian's The Best…


Book cover of Dopesick: Dealers, Doctors, and the Drug Company That Addicted America

Julie Salamon Author Of Unlikely Friends

From Julie's 3 favorite reads in 2023.

Why am I passionate about this?

Author Reader Adventurer Do-gooder History buff

Julie's 3 favorite reads in 2023

Julie Salamon Why did Julie love this book?

It’s hard to say I love this book because it is not an easy book to read—even though I read it compulsively.

Beth Macy is a great journalist who spent years covering the opioid crisis as it was developing. It is tricky to turn social ills into narratives in non-fiction, but Macy doesn’t use cheap tricks to grab her readers by the throat.

Her research and compassion—and well-placed anger—drive this investigation of a terrible epidemic driven by greed. Yet Macy paints with a nuanced brush, delving into the complexity of modern life that paved the way for this heartbreaking and horrifying scourge.

By Beth Macy,

Why should I read it?

3 authors picked Dopesick as one of their favorite books, and they share why you should read it.

What is this book about?

Journalist Beth Macy's definitive account of America's opioid epidemic "masterfully interlaces stories of communities in crisis with dark histories of corporate greed and regulatory indifference" (New York Times) -- from the boardroom to the courtroom and into the living rooms of Americans.
In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous…


Book cover of Empire of Pain: The Secret History of the Sackler Dynasty

Benjamin Breen Author Of Tripping on Utopia: Margaret Mead, the Cold War, and the Troubled Birth of Psychedelic Science

From my list on the history of drugs.

Why am I passionate about this?

As a historian of science and medicine, I’m fascinated by the many ways that drugs—from tea to opiates, Prozac to psychedelics—have shaped our world. After all, there are few adults on the planet today who don’t regularly consume substances that have been classified as a drug at one time or another (I’m looking at you, coffee and tea!). The books I’ve selected here have deeply influenced my own thinking on the history of drugs over the past decade, from my first book, The Age of Intoxication, to my new book on the history of psychedelic science.

Benjamin's book list on the history of drugs

Benjamin Breen Why did Benjamin love this book?

In this tour-de-force work of investigative journalism, New Yorker staff writer Patrick Radden Keefe traces the sordid history of the Sackler dynasty, the billionaire family behind Purdue Pharmaceuticals and its blockbuster narcotic painkiller OxyContin.

With both narrative verve and moral urgency—a combination that isn’t always easy to pull off—this book exposes one of the many points of origin for America’s devastating opioid epidemic. Keefe’s work has reinforced my conviction that drug historians have an important role to play in shaping public understanding and policy debates around these substances in the present. I found this book to be a page-turner and one of the most thoughtful books I’ve read in years.  

By Patrick Radden Keefe,

Why should I read it?

5 authors picked Empire of Pain as one of their favorite books, and they share why you should read it.

What is this book about?

NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing.

"A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate

The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom…


Book cover of Holden, After and Before: Love Letter for a Son Lost to Overdose
Book cover of The Last Exchange
Book cover of Pharma: Greed, Lies, and the Poisoning of America

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