The best books about the history of drugs

Why am I passionate about this?

As a historian of science and medicine, I’m fascinated by the many ways that drugs—from tea to opiates, Prozac to psychedelics—have shaped our world. After all, there are few adults on the planet today who don’t regularly consume substances that have been classified as a drug at one time or another (I’m looking at you, coffee and tea!). The books I’ve selected here have deeply influenced my own thinking on the history of drugs over the past decade, from my first book, The Age of Intoxication, to my new book on the history of psychedelic science.


I wrote...

Tripping on Utopia: Margaret Mead, the Cold War, and the Troubled Birth of Psychedelic Science

By Benjamin Breen,

Book cover of Tripping on Utopia: Margaret Mead, the Cold War, and the Troubled Birth of Psychedelic Science

What is my book about?

My book is a revisionist history of psychedelic research in the twentieth century. Centered on the pioneering anthropologist Margaret Mead and the circle of researchers she brought together, it explores how the concept of psychedelic therapy grew out of the utopian dreams and existential fears of the generation that came of age during World War II.

Along the way, readers meet a colorful cast of characters like John C. Lilly, who famously blended dolphin research with LSD experimentation. Though it details how psychedelic researchers became entangled with Cold War espionage, Tripping on Utopia is also a story of idealism. It reveals a fascinating and largely untold backstory for today’s psychedelic renaissance, offering important lessons for anyone interested in the field today.

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The books I picked & why

Book cover of Forces of Habit: Drugs and the Making of the Modern World

Benjamin Breen Why did I love this book?

If I were asked to recommend just one book on the history of drugs, this would be it. Courtwright is an expert in the history of drugs in the nineteenth and twentieth-century United States, but in this book, he zooms out—way out—to think about the larger history of humanity’s relationship to mind-altering substances.

At the book's core is Courtwright’s influential concept of a “psychoactive revolution” that influenced the histories of empire, globalization, and science over the past five centuries. I have been deeply influenced by his approach ever since I first read this book in grad school, and I use it often in my teaching. 

By David T. Courtwright,

Why should I read it?

2 authors picked Forces of Habit as one of their favorite books, and they share why you should read it.

What is this book about?

What drives the drug trade, and how has it come to be what it is today? A global history of the acquisition of progressively more potent means of altering ordinary waking consciousness, this book is the first to provide the big picture of the discovery, interchange, and exploitation of the planet's psychoactive resources, from tea and kola to opiates and amphetamines.


Book cover of Jungle Laboratories: Mexican Peasants, National Projects, and the Making of the Pill

Benjamin Breen Why did I love this book?

I admire the way that Jungle Laboratories weaves together the story of something globally famous—the birth control pill—with an untold history of a specific time and place in rural Mexico.

In this superbly researched book, Harvard History of Science professor Gabriela Soto Laveaga reveals how the yam fields of Veracruz became improbable sites of pharmaceutical innovation in the years during and after World War II. This book is a model of transnational history at its finest and a strikingly original take on the history of pharmacy, gender, labor, and global science. 

By Gabriela Soto Laveaga,

Why should I read it?

1 author picked Jungle Laboratories as one of their favorite books, and they share why you should read it.

What is this book about?

In the 1940s chemists discovered that barbasco, a wild yam indigenous to Mexico, could be used to mass-produce synthetic steroid hormones. Barbasco spurred the development of new drugs, including cortisone and the first viable oral contraceptives, and positioned Mexico as a major player in the global pharmaceutical industry. Yet few people today are aware of Mexico's role in achieving these advances in modern medicine. In Jungle Laboratories, Gabriela Soto Laveaga reconstructs the story of how rural yam pickers, international pharmaceutical companies, and the Mexican state collaborated and collided over the barbasco. By so doing, she sheds important light on a…


Book cover of A Thirst for Empire: How Tea Shaped the Modern World

Benjamin Breen Why did I love this book?

This ambitious and readable book explores how a seemingly simple beverage—tea—became a force shaping global empires. Rappaport, a historian at UC Santa Barbara, documents how tea has influenced everything from global trade networks and consumer cultures to ideas about health, morality, and national identity over the past three centuries.

Readers follow tea’s rise to become a key global commodity, moving from the courtly culture of tea in imperial China to the pages of Victorian magazines and the vast plantations of India and East Africa. This book made me think in a new way about the origins of modern-day consumer culture—not to mention the cup of tea I’m drinking as I write this. 

By Erika Rappaport,

Why should I read it?

2 authors picked A Thirst for Empire as one of their favorite books, and they share why you should read it.

What is this book about?

How the global tea industry influenced the international economy and the rise of mass consumerism

Tea has been one of the most popular commodities in the world. For centuries, profits from its growth and sales funded wars and fueled colonization, and its cultivation brought about massive changes-in land use, labor systems, market practices, and social hierarchies-the effects of which are with us even today. A Thirst for Empire takes an in-depth historical look at how men and women-through the tea industry in Europe, Asia, North America, and Africa-transformed global tastes and habits. An expansive and original global history of imperial…


Book cover of Psychonauts: Drugs and the Making of the Modern Mind

Benjamin Breen Why did I love this book?

Mike Jay is the best writer I know of when it comes to highlighting the human stories behind the history of drugs. He is also fabulously engaging and original.

Jay’s most recent book is a compelling history of self-experimentation with drugs, which ranges from Romantic-era opium eaters like Thomas de Quincey to pioneer neuroscientists and Siberian shamans—and, of course, the hilariously weird nitrous oxide experiments of William James, who graces the book’s cover. 

By Mike Jay,

Why should I read it?

1 author picked Psychonauts as one of their favorite books, and they share why you should read it.

What is this book about?

"Fascinating."-Thomas W. Hodgkinson, The Guardian

"Richly detailed and frequently illuminating."-Rhys Blakely, Times (UK)

"Excellent."-Clare Bucknell, New Yorker

A New Yorker Best of the Week Pick

A provocative and original history of the scientists and writers, artists and philosophers who took drugs to explore the hidden regions of the mind

Until the twentieth century, scientists investigating the effects of drugs on the mind did so by experimenting on themselves. Vivid descriptions of drug experiences sparked insights across the mind sciences, pharmacology, medicine, and philosophy. Accounts in journals and literary fiction inspired a fascinated public to make their own experiments-in scientific demonstrations,…


Book cover of Empire of Pain: The Secret History of the Sackler Dynasty

Benjamin Breen Why did I love this book?

In this tour-de-force work of investigative journalism, New Yorker staff writer Patrick Radden Keefe traces the sordid history of the Sackler dynasty, the billionaire family behind Purdue Pharmaceuticals and its blockbuster narcotic painkiller OxyContin.

With both narrative verve and moral urgency—a combination that isn’t always easy to pull off—this book exposes one of the many points of origin for America’s devastating opioid epidemic. Keefe’s work has reinforced my conviction that drug historians have an important role to play in shaping public understanding and policy debates around these substances in the present. I found this book to be a page-turner and one of the most thoughtful books I’ve read in years.  

By Patrick Radden Keefe,

Why should I read it?

4 authors picked Empire of Pain as one of their favorite books, and they share why you should read it.

What is this book about?

NEW YORK TIMES BESTSELLER • A NEW YORK TIMES NOTABLE BOOK OF THE YEAR • A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. From the prize-winning and bestselling author of Say Nothing.

"A real-life version of the HBO series Succession with a lethal sting in its tail…a masterful work of narrative reportage.” – Laura Miller, Slate

The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom…


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