The best medical thrillers featuring doctors and nurses behaving very, very badly

Why am I passionate about this?

I have always been fascinated by medicine and the people who are there to care for us when needed. I have worked as a nurse and midwife, and the thought that someone, anyone, could actively harm those in their care is horrific. But it happens. At first, I read medical thrillers as I would have read any murder mystery, but now, post-Shipman et al., I also want to know why they kill. I think that these books give us some ideas about this, but we can still never really know what goes on in the mind of a murderous doctor or nurse, and that’s what makes these books so thrilling. 


I wrote...

The Doctor

By Annie Payne,

Book cover of The Doctor

What is my book about?

Caregiver, life saver… or cold-blooded killer?

Running away from a troubled past, Doctor Alison Wilson has moved to a new town to take up the role of Chief Medical Officer at a failing hospital. Tasked with shaking things up, she quickly learns that things are worse than they initially seem: patient records are a mess, staff morale is low, and she slowly becomes sure that there is something much more sinister going on. As Alison starts to dig into the hospital’s past, she gradually discovers a trail of lies that runs deeper and darker than she could ever have imagined. There’s a cold-blooded killer in the hospital. And they have Alison in their sights.

Shepherd is reader supported. When you buy books, we may earn an affiliate commission.

The books I picked & why

Book cover of Coma

Annie Payne Why did I love this book?

Robin Cook is the Grandaddy of medical thriller writers, and I read this not long after it first came out. It is the chilling story of a medical student who investigates why normally fit and healthy patients are suddenly lapsing into coma. 

There is a strong and intelligent female protagonist, which is important to me. Yes, she can cry and even fall into the arms of a man, but she needs to be intelligent and stay strong, and Susan does that here. At the time, I was impressed by the level of authenticity but didn’t believe that anyone in the medical profession would ever deliberately hurt or kill their patients. Now, of course, we know better.

I re-read it before writing this and can honestly say that this book stands the test of time and is still relevant today.

By Robin Cook,

Why should I read it?

3 authors picked Coma as one of their favorite books, and they share why you should read it.

What is this book about?

The blockbuster bestseller that kickstarted a new genre--the medical thriller--is now available in trade paperback for the first time.
They called it "minor surgery," but Nancy Greenly, Sean Berman and a dozen others--all admitted to Boston Memorial Hospital for routine procedures--were victims of the same inexplicable, hideous tragedy on the operating table. They never woke up.
Susan Wheeler is a third-year medical student working as a trainee at Boston Memorial Hospital. Two patients during her residency mysteriously go into comas immediately after their operations due to complications from anesthesia. Susan begins to investigate the causes behind both of these alarming…


Book cover of Do No Harm

Annie Payne Why did I love this book?

This is the newest book I have chosen and is a slick psychological thriller where the doctor concerned is being forced to do something terrible. That’s not a spoiler; we know that from the very beginning.

The author manages to convey the very real horror of having to kill in order to save the life of a loved one, which is a more comforting thought than that the person we are trusting with our life might choose to take it on a whim.

The pace of this story is relentless, and the pressure that builds as the time for the terrible deed comes near is very deftly handled. It was a real page-turner that I read in one sitting.

By Jack Jordan,

Why should I read it?

1 author picked Do No Harm as one of their favorite books, and they share why you should read it.

What is this book about?

PRE-ORDER THE NEW JACK JORDAN NOVEL, CONVICTION, COMING IN PAPERBACK SPRING 2024

THE SUNDAY TIMES BESTSELLER AND WATERSTONES THRILLER OF THE MONTH

'Chilling and perfectly paced, one to put on the very top of your TBR!' Sarah Pearse
'Thriller fans will be in heaven' Louise Candlish

MY CHILD HAS BEEN TAKEN.
AND I'VE BEEN GIVEN A CHOICE . . .
KILL A PATIENT ON THE OPERATING TABLE
OR LOSE MY SON FOREVER.

The man lies on the table in front of me.
As a surgeon, it's my job to save him.
As a mother, I know I must kill him.…


Book cover of The Surgeon

Annie Payne Why did I love this book?

I liked this book firstly because of the level of authenticity, something that is very important as a nurse myself. The reader needs to be able to suspend disbelief and if there is a detail that is wrong, it becomes impossible to fully believe in the story. Getting this right requires a lot of research, particularly if the writer does not come from a medical background.

As with Jack Jordan’s book, I liked that the reader could feel sympathy for the surgeon, and could understand why she behaved as she did.

The story in this book also has some unexpected twists, and I enjoyed the tantalizing slow reveal of the back story so that the reader eventually comes to understand what has happened and why.

By Leslie Wolfe,

Why should I read it?

1 author picked The Surgeon as one of their favorite books, and they share why you should read it.

What is this book about?

Trusted surgeon. Loving wife. Murderer?

Before my world came crashing down, I had it all. The successful career I dreamed of. The beautiful red-brick home where I could relax in front of the fire. The handsome, devoted husband whose blue eyes and charming smile always made me feel safe.

As I call time of death, my voice is steady. My colleagues stand hushed around me, their eyes on me, confused, concerned.

I have never lost a patient until today.

My hands tremble inside their gloves. I slide down the cold tiled walls, my heart racing in my chest.

I have…


Book cover of The Certificate

Annie Payne Why did I love this book?

I have included this book because it was clear from page one that the author really knows how a GP surgery works and the role of the nurse. I wasn’t surprised to read in the author's note at the end that she didn’t publish this until after she had retired from her nursing role.

The detail of how she manages to steal a death certificate and the sheer deviousness involved rings very, very true. The story slowly moves from a “Is it possible?” to actually committing the act in a way that made riveting reading.

I also really liked the fact that the female protagonist was older and described as something of a plain Jane. It made her much easier to identify with (not that I would ever have considered killing a patient, honest!) 

By Priscilla Masters,

Why should I read it?

1 author picked The Certificate as one of their favorite books, and they share why you should read it.

What is this book about?

‘Plain Jane’ Ziegler has been a district nurse all her life...

All her life, she has been overlooked by difficult patients, disinterested colleagues and even her own family.

So when she discovers a way to commit the perfect crime, Jane seizes the opportunity and begins deliberating who of her many patients is most deserving of her murderous attention.

And when elderly James Walsh tries one to many times to proposition her, Jane seizes her chance.

Although Walsh’s mother seems unconvinced by Jane’s explanation of his death, no one else, least of all Jane’s fellow doctors, seems the least bit surprised.…


Book cover of The Nurse

Annie Payne Why did I love this book?

This book is different because the protagonist actually starts her murderous spree before she is a nurse and throughout the story, there are always good reasons for the crimes she commits, which helps you develop an understanding and even relate to her problems, if not her methods of dealing with them. Becoming a nurse just enables her sociopathic and psychopathic tendencies, which is very worrying.

The author is not from a medical background, but the nursing side is well-researched, even if I have a few questions about the authenticity of the medical aspects (like the actions of the drugs used.)

There are lots of twists and turns in this cat-and-mouse story as Lissa learns more about herself and the people she works alongside, which makes it a real page-turner.

By Valerie Keogh,

Why should I read it?

1 author picked The Nurse as one of their favorite books, and they share why you should read it.

What is this book about?

The NUMBER ONE bestselling psychological thriller from Valerie Keogh!

'Keogh is the queen of compelling narratives and twisty plots' Jenny O'Brien

'A wonderful book, I can't rate this one highly enough. If only there were ten stars, it's that good. Valerie Keogh is a master story-teller, and this is a masterful performance.' Bestselling author Anita Waller

Do No Harm...

Bullied, overlooked and under-appreciated, Lissa McColl learns at an early age to do very bad things.

As a nurse, she is respected and valued for the first time in her life. But Lissa hates her job and the selfish, rude and…


You might also like...

A Theory of Expanded Love

By Caitlin Hicks,

Book cover of A Theory of Expanded Love

Caitlin Hicks Author Of A Theory of Expanded Love

New book alert!

Why am I passionate about this?

My life and work have been profoundly affected by the central circumstance of my existence: I was born into a very large military Catholic family in the United States of America. As a child surrounded by many others in the 60s, I wrote, performed, and directed family plays with my numerous brothers and sisters. Although I fell in love with a Canadian and moved to Canada, my family of origin still exerts considerable personal influence. My central struggle, coming from that place of chaos, order, and conformity, is to have the courage to live an authentic life based on my own experience of connectedness and individuality, to speak and be heard. 

Caitlin's book list on coming-of-age books that explore belonging, identity, family, and beat with an emotional and/or humorous pulse

What is my book about?

Trapped in her enormous, devout Catholic family in 1963, Annie creates a hilarious campaign of lies when the pope dies and their family friend, Cardinal Stefanucci, is unexpectedly on the shortlist to be elected the first American pope.

Driven to elevate her family to the holiest of holy rollers in the parish, Annie is tortured by her own dishonesty. But when “The Hands” visits her in her bed and when her sister finds herself facing a scandal, Annie discovers her parents will do almost anything to uphold their reputation and keep their secrets safe. 

Questioning all she has believed and torn between her own gut instinct and years of Catholic guilt, Annie takes courageous risks to wrest salvation from the tragic sequence of events set in motion by her parents’ betrayal.

A Theory of Expanded Love

By Caitlin Hicks,


5 book lists we think you will like!

Interested in nursing, Boston, and presidential biography?

10,000+ authors have recommended their favorite books and what they love about them. Browse their picks for the best books about nursing, Boston, and presidential biography.

Nursing Explore 27 books about nursing
Boston Explore 175 books about Boston
Presidential Biography Explore 18 books about presidential biography