The most compelling medical nonfiction books

My mother was a Freudian psychiatrist who prescribed antidepressants as a last resort, while my brother, also a psychiatrist, turns to antidepressants as first-line therapy. I wanted to learn more about why my family members took these different approaches.

Before Prozac is a wonderful history and behind-the-scenes look at the medical treatment of depression and related disorders. I learned about the politics behind restricting access to benzodiazepines (like Valium®), how Prozac® was designed to be an anti-histamine until Lilly found a better indication and much more.

This is the first book I recommend to my friends who have a personal or academic interest in depression. I couldn’t put it down and suggest it to friends who are interested in the history of modern medicine. 

Like most people, the two diseases of aging that scare me the most are ischemic stroke and Alzheimer’s disease. I don’t want to lose my ability to think, and I want to preserve my memory. So...there is no time like the present to explore what I can do to learn how to prevent Alzheimer’s disease.

Bredesen is the first neuroscientist I’ve encountered who describes different types of Alzheimer’s and offers practical diagnostic and dietary advice. I’ve explored his recommendations, and I think they’re sound. I’ve suggested this to many of my friends for them and/or for their parents and loved ones.

Paganini was an extraordinary violinist because of his exceptionally flexible thumb. Why was his thumb so “bendy”? Genetics. His genes provided an opportunity, and he learned how to exploit it.

Each of us is genetically unique. Our challenge is to understand our genes, which can be positive or negative. The Violinist’s Thumb is a nice introduction to the importance of DNA and the impact of genes in history. Inbreeding in the European royals led to hemophilia and ultimately contributed to the fall of the Czar and the Russian Empire. Genes have played a major role in history, art, and science.

It is a fun book with a novel perspective. 

There is nothing that worries me more than when I hear that someone has been transferred to the intensive care unit with an infectious disease.

There are reasonable, not perfect, treatments and approaches to treat bacterial infections—although they are becoming fewer and fewer. Rarely discussed is the threat of fungal infection with Candida auris in hospitals—a treatment-resistant and hearty strain that is infecting and taking the lives of immunocompromised or weakened patients in the hospital. Unlike bacteria and viruses, fungi are resilient and can remain dormant in many environments. It is not just hospitals where fungi are dangerous; they can infect the lungs of desert dwellers and cause destruction in forests.

I suggest this book to my friends who want to be aware and take precautions (as much as possible) and encourage pharma and biotech to develop new tools/medicines to control deadly hospital infections.

Who doesn’t love a true story of David and Goliath? Who really believes that the inventor of the “better mousetrap” always wins? This is a real-life medical thriller when the properties of a mineral were found to be a cheaper, better solution to stopping battlefield bleeding.

The “Davids” took on “Goliath,” who supported their vested interests in an inferior product that cost the lives of infantrymen. It took a courageous whistle-blower to come forward and change the trajectory. Ultimately the mineral was adopted and used effectively in the Iraq War. The better trauma medicine won, but it took years. The story is, sadly, all too real—but good does triumph!