Madness and Memory

By Stanley B. Prusiner,

Book cover of Madness and Memory: The Discovery of Prions--A New Biological Principle of Disease

Book description

A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases

In 1997, Stanley B. Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the…

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1 author picked Madness and Memory as one of their favorite books. Why do they recommend it?

Stan Prusiner received the Nobel Prize of Medicine in 1997 for identifying what at the time was considered a novel mechanism of neurodegeneration: the prions. These “infectious proteins” were responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease. Although I have come to doubt that prions are a cause of rapidly progressive dementia and may instead represent a consequence, Prusiner’s memoir is filled with moments of skepticism, self-doubt, adversity, and intellectual rivalries –the ingredients for a gripping drama in neurosciences. 

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