100 books like The Violinist's Thumb

This book not only provides a fascinating look at how we actually digest food, pluck out essential nutrients, and produce poop from the leftovers passing through the gut, but also includes charming and witty illustrations of many of these steps by the author’s sister, Jill.

An entire book about the gut? Yes, and it’s so interesting, with some gentle humor and well-thought-out analogies that help demystify what you’ll come to believe is a superhero of an organ.

I made notes, highlighted particularly illuminating sections, and found myself saying, “Wow! I didn’t know that!” throughout the book. It definitely gave me a new sense of wonder and appreciation for the intricate abilities of my own body.

Let’s be honest. Books about science usually fall into one of two categories. Many of them are dry and boring, with way too much detail, losing the reader in the scientific weeds. Other times they are too fluffy, with the author trying so hard to be witty and cool that the science takes a back seat.

It is rare to find an author and a book that can bring modern, complex science to the table in a package that is witty, readable, and engaging. Jeremy DeSilva pulls this off in First Steps. DeSilva, one of the world’s preeminent paleoanthropologists, uses his vast experience in the field to explain both how and why humans started walking upright.

There is no better book that combines the worlds of science and sports than The Sports Gene by David Epstein.

This book takes you all around the world to explore the physical and mental traits of diverse athletes with the goal of understanding how much of athletic prowess is written in our genetic code. The results are surprising and will flip a lot of your preconceived notions about nature and nurture.

I read it years ago but still talk to my students every semester about why, year in and year out, the best distance runners in the world seem to keep coming from the same little pocket of Kenya.

Diseases are frequently handled as though they are just "out of the condition" and considered as such.

This frequently results in a superficial understanding of the underlying causes of the disorders. In an effort to explore the problem from an evolutionary standpoint, Zoobiquity takes readers to many diseases occurring in both animals and humans, showing their shared roots.

It's an eye-opener for readers who aren't familiar with evolutionary medicine with a clear implication for how we can tackle human diseases more effectively.

The new science of DNA reveals a lot about how we think about identity.

Humans are a migratory species and our stories are complicated. Ancient DNA don't always match people's stories about their ancestors. Rather than being in a place for thousands of years, sometimes we replaced those who were there before or only the males of the group.

Sometimes we completely replaced the group that was there before but the original group's culture persisted or even replaced the invading culture. The book complicates our understanding of indigeneity and belonging.

It is hard to believe that Matt Ridley’s grand tour of the human genome was published back in 1999. Yet even today, more than two decades later, Ridley’s engaging, chromosome by chromosome investigation of our genetic make-up remains a marvel that has never been equaled. From the genes that enable the most basic chemical processes in our cells to those that determine our height and eye color, the mysterious “junk DNA” that lives between our genes, and speculation about the ways that genes affect personality, behavior, and society, Ridley brings science to life in this engaging and timeless book.

This book starts and ends with the story of Dr. Jiankui He, the infamous Chinese researcher responsible for the first CRISPR experiment resulting in genetically modified children.

It chronicles Dr. He’s “meteoric rise to fame” followed by his “dramatic fall from grace.”

In telling this story Kirksey, a cultural anthropologist, entertains the reader with details about interesting characters he meets and places he visits in his quest to both situate this debacle in relation to earlier efforts at genetic engineering and cell therapy in the United States and to confirm some of the contested details about what did or did not happen in China in the years leading up to this “first”.

Along the way, Kirksey lays bare salient facts about conflicts of interests among scientists, the corporate world’s vaunted pursuit of profit, and the ways in which nationalistic aspirations seed unhealthy competition.

All of Powers’ books are brilliant, for all kinds of reasons. I remember this book when it first came out decades ago. First of all, it’s just great entertainment, a great story with rich characters. Then, at the same time, Powers captures the beauty of science and discovery as he immerses the reader in the time after the discovery of the double-helical structure of DNA when there was a mad rush to figure out how DNA could encode proteins. Powers captures it all and gets the science right and brings in similarities between the DNA code and music and captures what it’s like working in a lab. How is this possible?

I love the way that this book puts solving the genetic code in the context of the development of the "information age" in the 1950s.

This book explains the origins of the popular (but wrong) idea that DNA is the "book of life" and some sort of advanced information system. I call this a ‘one-dimensional’ view of life (as opposed to a four-dimensional view, which takes into account not just sequence but secondary and tertiary structures and how they change with time).

I use this book in my introductory bioinformatics lectures to help get across the "new" concept that, contrary to popular cultural beliefs, DNA is not a language, nor is it a 'sophisticated computer code’. Biology is messy and complicated and very much contextual.

I guess this book is officially qualified as ‘science fiction’ but I think of it instead as great fiction that appreciates and then grabs the very edges of our current knowledge and extends them like a wild rubber band in ways that captivate. Bear takes some of the guesses and hints about what lies within the 95% of our DNA that at first seems to have no clear ‘purpose’ and imagines it is part of a sensor that is able to catalyze the creation of new versions of life in response to the kinds of dramatic stressors— climate change, etc— that humans have made for ourselves.