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Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing Paperback – May 11, 2021

4.4 4.4 out of 5 stars 171 ratings

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One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine.

If our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease.

But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change.

Engrossing and page-turning,
Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code.

Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.

Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In
Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.
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Editorial Reviews

About the Author

Kevin Davies is the executive editor of The CRISPR Journal and the founding editor of Nature Genetics. He holds an MA in biochemistry from the University of Oxford and a PhD in molecular genetics from the University of London. He is the author of Cracking the Genome, The $1,000 Genome, and co-authored a new edition of DNA: The Story of the Genetic Revolution with Nobel Laureate James D. Watson and Andrew Berry. In 2017, Kevin was selected for a Guggenheim Fellowship in science writing.

Product details

  • Publisher ‏ : ‎ Pegasus Books (May 11, 2021)
  • Language ‏ : ‎ English
  • Paperback ‏ : ‎ 464 pages
  • ISBN-10 ‏ : ‎ 1643137638
  • ISBN-13 ‏ : ‎ 978-1643137636
  • Item Weight ‏ : ‎ 15.2 ounces
  • Dimensions ‏ : ‎ 5.5 x 1.4 x 8.25 inches
  • Customer Reviews:
    4.4 4.4 out of 5 stars 171 ratings

About the author

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Kevin Davies
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Kevin Davies is a British science journalist and editor. He is currently the executive editor of The CRISPR Journal, based in New York. Kevin studied at Oxford University and moved to the U.S. in 1987 after earning his PhD in genetics. He is the founding editor of the journal Nature Genetics and Bio-IT World magazine, former editor-in-chief of Cell Press, and the first publisher of C&EN, the weekly magazine of the American Chemical Society.

"EDITING HUMANITY" is Kevin's fourth book, and first for Pegasus Books. He published "The $1,000 Genome" in 2010 and "Cracking the Genome," about the race for the Human Genome Project, in 2000. His first book, "Breakthrough," co-authored with the late Michael White, was about the race to identify the "breast cancer gene". That resulted in Kevin serving as technical consultant for the 2013 movie Decoding Annie Parker, starring Helen Hunt, Samantha Morton and Aaron Paul. He's also a co-author with Jim Watson and Andrew Berry of "DNA: The story of the Genetic Revolution" (Knopf, 2017).

Customer reviews

4.4 out of 5 stars
4.4 out of 5
171 global ratings
For The Gene Editing Connoisseur | Delightfully Written, with Wit — & — Precision Vocabulary | Bravo
5 Stars
For The Gene Editing Connoisseur | Delightfully Written, with Wit — & — Precision Vocabulary | Bravo
Kevin Davies is Founding Executive Editor of The CRISPR Journal, which, as they proudly proclaim, is the first and only peer viewed scientific journal dedicated to the gene editing. I have been a HUGE FAN of Mr. Davies for approximately thirty days. Through the Investor Relations site of publicly traded gene editing company based in Durham, I stumbled upon the free registration landing page for the International CRISPR Gene Editing Symposium which was held on Wednesday, September 23, 2020, virtually.__________ __________ __________SaturdayJanuary 16, 202110:00 PMI — Love — how apparent it is how much Mr. Davies himself loves this brave new world of genome and life altering editing technologies. He has been observing tectonic changes in our understanding of life, from a front row vantage point, for his entire professional career, and through his beautifully written, and witty, poetic prose, he invites us to reflect upon the infinitesimal history yet momental importance of the business history of CRISPR and economics of the science of life.Highly recommend this book!BLUE ROOM (TM) Reading List:Life SciencesBiotechnologyGenome EditingJanuary 23, 2021
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Top reviews from the United States

Reviewed in the United States on January 24, 2024
I flunked out of Chemistry, so to have this guy be able to explain very confusing and novel BioChem breakthroughs to the point I could catch the gist is saying something! I purchased this book because I heard about CRISPR offhand and had no idea what it was or the implication for the future. I don't work in this field at all, and now I'm recommending this book to all of my friends because of what a fascinating read it is, and how knowledgeable (and humorous) the author is. This was my first book that I read by Davies, and I'm excited to catch up with his other works.

The only thing that I think this book would have benefitted from, is if he leaned in on some of the more negative possible outcomes of CRISPR or germline editing in general. He certainly does acknowledge them in his book, and does go into some detail, but I could tell that he is mainly approaching the topic with his scientific research hat on. I think it would have been cool to dive deeper into the ways some governments could use CRISPR for unethical purpose, but could also understand that could lead to fear-mongering, which was rightly criticized in the book for leading to overcorrection and a lack of scientific progress (more tastefully then I've put it here).

Overall great read, and you don't have to be an expert (or even a novice) in the field to enjoy it.
2 people found this helpful
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Reviewed in the United States on October 9, 2020
Genome editing did not need Drs. Doudna and Charpentier's well-deserved Nobel win to validate it. Though fraught with potential for ethical abuse (something Davies attacks and parses fairly), CRISPR will seem to be one of those things that ends up changing lives and saving lives via "days of small things." Sickle cell and genetically adaptive crops, rare genetic disorders no longer causing families to suffer. While the birth of the "CRISPR babies" also made my stomach turn, I know that if I had a child suffering from the ravages of sickle cell, I would be first in line for treatment. Davies shows how the story of CRISPR is a human one--the scientists who have played a role in it's development over the years, the journalists who broke the news--with all their quirks, genius, and foibles. And he does not reduce Lulu and Nana—the babies born with genes edited by He Jianuki—to hashtags. These are real little girls and Davies tells their story with great humanity. A must-read to understand this scientific and medical innovation beyond hashtags and headlines.
20 people found this helpful
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Reviewed in the United States on June 19, 2023
Though the book at times gets too deeply into details for a lay audience, it’s a worthwhile read. The editing and proofreading was quite poor, though. There are multiple errors in every chapter. Though the errors don’t directly affect the content, they become annoying and cause the work to seem amateurish.
One person found this helpful
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Reviewed in the United States on January 7, 2024
My nerdy kids didn't want video games but asked Santa for a book called Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing. I can't through a whole page without feeling dumb but these kids have loved it!
Reviewed in the United States on October 26, 2020
Davies is an exceptional author on par with Isaacson for his ability to create a movingly rich picture of scientific evolution while not losing the reader in technical jargon. Book offers a tremendous insight on CRISPR technologies but also a generous dose of what has to be thought through as a society to properly utilize nature’s secrets. As one would expect great science needs significant peripheral support to be accepted and regulated appropriately. CRISPR is no different.
5 people found this helpful
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Reviewed in the United States on November 17, 2020
As a layman, I recommend this book to anyone curious about what CRISPR is and what it promises, but read the Kindle version if you can. The book suffers, like most explanations by experts for non-experts, from the assumption of the author that he is talking to an audience that is as familiar with relevant scientific principles and terminology as he is himself. For me, there was lots to look up, a lot that needed to be explained, and the search features of the Kindle were invaluable for this.

Also, there is much in the book that I found irrelevant. Too lengthy discussion of He Jianqui’s crime of making three “CRISPR babies” for example, the ethics of CRISPR use, and the infighting of the scientists looking for big paydays for their discoveries – all interesting subjects, but taking up more space than they should have that should have been used in better clarifying the mechanisms of CRISPR Cas 9 itself.

Davies discusses and provides a link to the documentary film "Human Nature" about CRISPR. Watch it. It’s an invaluable clarification of the subject that will add much to the reading of the book.
5 people found this helpful
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Reviewed in the United States on January 17, 2021
Kevin Davies is Founding Executive Editor of The CRISPR Journal, which, as they proudly proclaim, is the first and only peer viewed scientific journal dedicated to the gene editing. I have been a HUGE FAN of Mr. Davies for approximately thirty days. Through the Investor Relations site of publicly traded gene editing company based in Durham, I stumbled upon the free registration landing page for the International CRISPR Gene Editing Symposium which was held on Wednesday, September 23, 2020, virtually.
__________ __________ __________

Saturday
January 16, 2021
10:00 PM

I — Love — how apparent it is how much Mr. Davies himself loves this brave new world of genome and life altering editing technologies. He has been observing tectonic changes in our understanding of life, from a front row vantage point, for his entire professional career, and through his beautifully written, and witty, poetic prose, he invites us to reflect upon the infinitesimal history yet momental importance of the business history of CRISPR and economics of the science of life.

Highly recommend this book!

BLUE ROOM (TM) Reading List:
Life Sciences
Biotechnology
Genome Editing
January 23, 2021
Customer image
5.0 out of 5 stars For The Gene Editing Connoisseur | Delightfully Written, with Wit — & — Precision Vocabulary | Bravo
Reviewed in the United States on January 17, 2021
Kevin Davies is Founding Executive Editor of The CRISPR Journal, which, as they proudly proclaim, is the first and only peer viewed scientific journal dedicated to the gene editing. I have been a HUGE FAN of Mr. Davies for approximately thirty days. Through the Investor Relations site of publicly traded gene editing company based in Durham, I stumbled upon the free registration landing page for the International CRISPR Gene Editing Symposium which was held on Wednesday, September 23, 2020, virtually.
__________ __________ __________

Saturday
January 16, 2021
10:00 PM

I — Love — how apparent it is how much Mr. Davies himself loves this brave new world of genome and life altering editing technologies. He has been observing tectonic changes in our understanding of life, from a front row vantage point, for his entire professional career, and through his beautifully written, and witty, poetic prose, he invites us to reflect upon the infinitesimal history yet momental importance of the business history of CRISPR and economics of the science of life.

Highly recommend this book!

BLUE ROOM (TM) Reading List:
Life Sciences
Biotechnology
Genome Editing
January 23, 2021
Images in this review
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One person found this helpful
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Reviewed in the United States on July 28, 2022
An excellent read. Gives a very good history of CRISPR and all the important players.
2 people found this helpful
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Geoffrey Jelley
4.0 out of 5 stars Good read
Reviewed in Canada on January 2, 2022
Worth reading
Awesome girl
5.0 out of 5 stars Interesting
Reviewed in Germany on April 26, 2021
With so much Curiosity I've ordered this book and I can't wait to satisfy my curiosity while unraveling the unending knowledge of CRISPR 😊😊😊😊😊😊😊
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Awesome girl
5.0 out of 5 stars Interesting
Reviewed in Germany on April 26, 2021
With so much Curiosity I've ordered this book and I can't wait to satisfy my curiosity while unraveling the unending knowledge of CRISPR 😊😊😊😊😊😊😊
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Cavallini Cristiano
3.0 out of 5 stars BISOGNA MIGLIORARE GLI IMBALLI
Reviewed in Italy on December 6, 2020
Pacco arrivato completamente aperto: per fortuna il libro è integro.
Devo aggiungere che ultimamente gli imballi sono decisamente scadenti e non idonei.
Non è la prima volta che la merce acquistata su Amazon arriva con imballi devastati e il contenuto è poco protetto.