$24.70
$11.50 delivery June 3 - 25. Details
Only 2 left in stock - order soon.
$$24.70 () Includes selected options. Includes initial monthly payment and selected options. Details
Price
Subtotal
$$24.70
Subtotal
Initial payment breakdown
Shipping cost, delivery date, and order total (including tax) shown at checkout.
Ships from
New books from Germany
Ships from
New books from Germany
Returns
Eligible for Return, Refund or Replacement within 30 days of receipt
Eligible for Return, Refund or Replacement within 30 days of receipt
This item can be returned in its original condition for a full refund or replacement within 30 days of receipt. You may receive a partial or no refund on used, damaged or materially different returns.
Returns
Eligible for Return, Refund or Replacement within 30 days of receipt
This item can be returned in its original condition for a full refund or replacement within 30 days of receipt. You may receive a partial or no refund on used, damaged or materially different returns.
Payment
Secure transaction
Your transaction is secure
We work hard to protect your security and privacy. Our payment security system encrypts your information during transmission. We don’t share your credit card details with third-party sellers, and we don’t sell your information to others. Learn more
Payment
Secure transaction
We work hard to protect your security and privacy. Our payment security system encrypts your information during transmission. We don’t share your credit card details with third-party sellers, and we don’t sell your information to others. Learn more
Kindle app logo image

Download the free Kindle app and start reading Kindle books instantly on your smartphone, tablet, or computer - no Kindle device required.

Read instantly on your browser with Kindle for Web.

Using your mobile phone camera - scan the code below and download the Kindle app.

QR code to download the Kindle App

Something went wrong. Please try your request again later.

Wonder Drug: The Hidden Victims of America's Secret Thalidomide Scandal Paperback

4.7 4.7 out of 5 stars 146 ratings

Great on Kindle
Great Experience. Great Value.
iphone with kindle app
Putting our best book forward
Each Great on Kindle book offers a great reading experience, at a better value than print to keep your wallet happy.

Explore your book, then jump right back to where you left off with Page Flip.

View high quality images that let you zoom in to take a closer look.

Enjoy features only possible in digital – start reading right away, carry your library with you, adjust the font, create shareable notes and highlights, and more.

Discover additional details about the events, people, and places in your book, with Wikipedia integration.

Get the free Kindle app: Link to the kindle app page Link to the kindle app page
Enjoy a great reading experience when you buy the Kindle edition of this book. Learn more about Great on Kindle, available in select categories.
{"desktop_buybox_group_1":[{"displayPrice":"$24.70","priceAmount":24.70,"currencySymbol":"$","integerValue":"24","decimalSeparator":".","fractionalValue":"70","symbolPosition":"left","hasSpace":false,"showFractionalPartIfEmpty":true,"offerListingId":"XLprZZIV1JZHAEcrlsW%2Bq102B3JM6EFiPXOwHkdWGmlPGXpenBzpLo6daL7MSeRcvslYg4822WNt%2BQeby1bDKTxJP32Ul2%2FHjaduT71Cdzd3PYi57idjmQ8pqJwXb9kFETHymDfej355XCQBebN7JQu0BrGpkZBPzUoWdQ4hVI5lZJsx8ASoszUw9zYkfWQq","locale":"en-US","buyingOptionType":"NEW","aapiBuyingOptionIndex":0}]}

Purchase options and add-ons


The Amazon Book Review
The Amazon Book Review
Book recommendations, author interviews, editors' picks, and more. Read it now.

Product details

  • Language ‏ : ‎ English
  • ISBN-10 ‏ : ‎ 0008295700
  • ISBN-13 ‏ : ‎ 978-0008295707
  • Item Weight ‏ : ‎ 1.23 pounds
  • Dimensions ‏ : ‎ 6.02 x 1.42 x 9.21 inches
  • Customer Reviews:
    4.7 4.7 out of 5 stars 146 ratings

About the author

Follow authors to get new release updates, plus improved recommendations.
Jennifer Vanderbes
Brief content visible, double tap to read full content.
Full content visible, double tap to read brief content.

Jennifer Vanderbes is novelist, journalist and screenwriter whose work has been translated into sixteen languages. Her writing has appeared in The New York Times, The Wall Street Journal, The Washington Post, The Atlantic, and Granta. She has received awards from the Guggenheim Foundation, the New York Public Library, the Sloan Foundation, the National Endowment for the Humanities and the New York Council for the Arts. She lives in New York City with her daughters.

For more information visit www.jennifervanderbes.com

Customer reviews

4.7 out of 5 stars
4.7 out of 5
146 global ratings
Amazing -- a must-read
5 Stars
Amazing -- a must-read
"Wonder Drug" leaps off the pages, and is an amazing chronicle of the story of thalidomide in the U.S. and the world. It's a page turner -- fast paced, with dynamic characters -- and while it reads as easily and and compellingly as fiction, it's a true story. Jennifer Vanderbes spent years researching this book, and crafted a narrative as compelling as her earlier (also fabulous) novels. I cannot recommend it enough -- it will blow you away. Laughs, tears, pride, horror -- often in the same vignettes. Despite unfolding decades ago, the story remains timely. (I recently watched the new adaptation of "The Fall of The House of Usher," and some of the very same themes of drug development and safety echo throughout both tales.) The heroes and survivors both will amaze you with their determination; this book is (with no exaggeration) about the triumph of the human spirit. It's a mystery, but also a history: of feminism, science, medical ethics, and business corruption, all in one. Best of all, Vanderbes sticks the landing by introducing us to the survivors of this drug, their bravery (them and their families), and their inspirational stories of success. This book is amazing and important. Read it -- you will NOT be disappointed.
Thank you for your feedback
Sorry, there was an error
Sorry we couldn't load the review

Top reviews from the United States

Reviewed in the United States on December 11, 2023
"Wonder Drug" leaps off the pages, and is an amazing chronicle of the story of thalidomide in the U.S. and the world. It's a page turner -- fast paced, with dynamic characters -- and while it reads as easily and and compellingly as fiction, it's a true story. Jennifer Vanderbes spent years researching this book, and crafted a narrative as compelling as her earlier (also fabulous) novels. I cannot recommend it enough -- it will blow you away. Laughs, tears, pride, horror -- often in the same vignettes. Despite unfolding decades ago, the story remains timely. (I recently watched the new adaptation of "The Fall of The House of Usher," and some of the very same themes of drug development and safety echo throughout both tales.) The heroes and survivors both will amaze you with their determination; this book is (with no exaggeration) about the triumph of the human spirit. It's a mystery, but also a history: of feminism, science, medical ethics, and business corruption, all in one. Best of all, Vanderbes sticks the landing by introducing us to the survivors of this drug, their bravery (them and their families), and their inspirational stories of success. This book is amazing and important. Read it -- you will NOT be disappointed.
Customer image
5.0 out of 5 stars Amazing -- a must-read
Reviewed in the United States on December 11, 2023
"Wonder Drug" leaps off the pages, and is an amazing chronicle of the story of thalidomide in the U.S. and the world. It's a page turner -- fast paced, with dynamic characters -- and while it reads as easily and and compellingly as fiction, it's a true story. Jennifer Vanderbes spent years researching this book, and crafted a narrative as compelling as her earlier (also fabulous) novels. I cannot recommend it enough -- it will blow you away. Laughs, tears, pride, horror -- often in the same vignettes. Despite unfolding decades ago, the story remains timely. (I recently watched the new adaptation of "The Fall of The House of Usher," and some of the very same themes of drug development and safety echo throughout both tales.) The heroes and survivors both will amaze you with their determination; this book is (with no exaggeration) about the triumph of the human spirit. It's a mystery, but also a history: of feminism, science, medical ethics, and business corruption, all in one. Best of all, Vanderbes sticks the landing by introducing us to the survivors of this drug, their bravery (them and their families), and their inspirational stories of success. This book is amazing and important. Read it -- you will NOT be disappointed.
Images in this review
Customer image
Customer image
6 people found this helpful
Report
Reviewed in the United States on August 11, 2023
Jennifer Vanderbes's Wonder Drug is an enthralling, impossible-to-put-down exploration of one of the great tragedies perpetuated by drug companies upon unsuspecting (and trusting) victims. The drug, Thalidomide (sold and "freely" distributed under various names and derivatives as a sedative in the late 1950s and early 1960s), caused phocomelia (a shortening of the "limb/s being reduced or missing and leaving distal elements (handplate) in place" (National Institutes of Health). If you've ever seen a thalidomide baby, you've likely seen a photograph of a baby with "flipper-like" hands and/or feet. Many of those babies are now in their sixties; plenty died or were forgotten about once they were born, swaddled and pulled from their mothers and either put in homes or taken care of in other ways.

The William S. Merrell Company had been inundating medical facilities with pills that were causing severe birth defects, passing the pills off as remedies for such things as insomnia, morning sickness, and headaches, and it indeed felt like a "wonder drug." But the truth of that wonder drug was far from what was being claimed. It soon became apparent that “ten thousand babies worldwide” at the time were killed or born with deformed limbs and/or defective organs due to the drug. As I read these facts and as a father myself, I couldn’t fathom what these parents had gone through. It angered me.

The evolution and importance of the FDA, and how it altered the safety of the American public, materialized during the time of the thalidomide tragedy. But it was a slow process.

The story of thalidomide as a tested and effective drug reviewed by doctors and scientists was horrific. From Nazi experimentation with the drug in concentration camps to a lack of due diligence by the gatekeepers of healthcare around the globe, patients seeking relief from various ailments were treated as Guinea pigs. Many of them died, yet doctors continued to prescribe the drug, even before animal testing was completed, if any testing was ever completed at all. To say that the industry dropped the ball would be to put it mildly. But no one seemed to care, except a brave, inquisitive, and tough Dr. named Frances Kelsey, who brought thalidomide's dangers to light and pushed for its halt as the drug of choice for so many doctors.

The scientific evaluations being done were too rushed, but, for the drug companies, the profits were too tempting. Inevitably, due to the rules of the game at the FDA, those testing the medications had 60 days to kill them. But 60 days often wasn’t enough time to conduct the trials. And so the runaway trains of profit over people were set free.

The reality was that the politics of the early days of the FDA and its association with the drug manufacturers it was supposedly overseeing was not what it is today. What it was during the days of thalidomide's introduction into the hands of patients can be considered criminal. Profits above human decency seemed the norm. Trials were either not performed, performed inadequately, or simply overlooked in terms of what the actual results were. Thalidomide, or Kevadon, as it was called by the drug manufacturer Richardson-Merrell, was pushed to the public the way a street corner drug dealer pushes their product to their neighborhoods—except it was much worse, because Merrell had the financial ability to market their drugs heavily, all while sending an army of detail men (sales reps) to supplement demand.

Time and again, the need, or the results, of safety research, was sidelined, all for the profit of the companies hawking pills that would ultimately be proven lethal or extremely damaging, in particular to the unborn children of women given the medicine.

Vanderbes is brilliant at breaking down the way the medicine makes its way from the manufacturer to the detail men, to the receptive doctors or "clinical investigators" who would provide the drugs to their patients (these doctors were known as Dr. Backslappers), who then prescribed the meds to patients (or passed them along to other doctors, who were not clinical investigators), effectively making it impossible for accountability if anything went wrong, as the chain of custody of the medicine was lost.

In the hurricane of drug pushing for profit, ethical, detail-oriented doctors at the FDA like Dr. Frances Kelsey, sought to put a stop to the Wild Wild West days of profits over patients.

Yet the immorality of some of the doctors involved with the thalidomide tragedy, including a thoroughly repugnant study they executed on minors with brain damage in Bonn, Germany (where the drug was known as Contergan) is mind-boggling. That so many doctors went along with human trials of a drug proving fatal to so many will leave the reader not only astonished but wondering how such a thing could happen at all.

But what Vanderbes does so well is shed light on exactly how something so horribly wrong and unethical could happen in the shadow of WWII and in the 20th century, given all the progress the world had made. Shady business relationships between medical companies and medical journals was one factor that contributed to the problem. Another was that doctors who wished to publish their findings about the harmful effects of Thalidomide were often “delayed.” Yes, the world was different back then, but one has to ask themselves, Where was the decency? Where was the morality of all involved? Had these people and companies no shame?

Time after time after time, the drug companies selling Thalidomide hid any mention of safety findings related to the cash cow drug lining their pockets. Some of the companies outright lied, or contrived ways to get around halting the sale of it, which, by 1961, was in about 42 countries. Babies were being born with extremely malformed limbs and other birth defects, and the mothers and families of these children were being kept in the dark as to why. Responsibility was a game of hot potato no one wanted to play. so no one was held to account. Not the doctors, who didn’t have to tell patients what they were giving them, nor that the drugs they were being given had reported birth abnormalities, not the drug companies, who misled the FDA, nor, it seemed, anybody else involved with the spread of the wonder drug.

To mitigate the losses that acknowledging the drug's issues might cause, A Merrell press release “affirmed that thalidomide was ‘never sold in the United States.’" But as Vanderbes makes clear, “sold” did not mean not distributed. "At the time of Merrell’s “premarket distribution of [thalidomide, it was] . . . the largest in U.S. history.”

But then, in 1960, things began to change. A paper was published in the British Medical Journal, and the FDA in America caught on. Merrell was eventually found to have put the drug out into the market and then suppressed data and submitted false data in its Kevadon application. More companies followed suit. Once it was abundantly clear that the house of cards would fall, Grunenthal, the German seller of the drug, settled with its affected patients, rather than go to trial. But the damage was done. 150,000 worldwide victims were affected, 45 nations had thalidomide in circulation, and, in effect, it was still the Wild Wild West on who had thalidomide and where it was still being prescribed (or given out).

While Thalidomide was later found to be beneficial for treating certain symptoms of AIDS and leprosy, the WHO (the World Health Organization) put the kabash on its use due to “murky” research on the drug’s efficacy. Things have changed recently with how thalidomide and its variants are used, but none of this changes what happened to the thousands upon thousands of victims whose lives were either cut short or adversely affected for the duration of their entire lives.

Vanderbes's book is a must read, especially if you want to get a detailed understanding of how drug companies used to work (and hopefully a reminder of how things have changed since those days). It's also a history lesson in what women had to do in order to succeed in educational and career opportunities where the organizations they wanted to be a part of were overwhelmingly chauvanistic. The drug companies and even the FDA were geared towards men, directed by men, and the entire industry was controlled by the profit specific men reaped through the sale of thalidomide and other drugs. Women like Dr. Frances Kelsey and others paved the way for change. They were the champions of patients being lied to, manipulated, and physically and mentally affected by everything the drug companies in their quest for profits brought down upon them with neither their consent nor knowledge. What happened to the patients of thalidomide is horrific, and Vanderbes's book is a testament to why such a travesty should never happen again. Buy the book, and read it. Now. As a participant in the health industry, whether as a patient, a doctor, or any other role you may hold when it comes to healthcare, you should be aware of the history of thalidomide, if even just to know what to look out for any time a doctor says, "I'd like to prescribe you this . . . ."
17 people found this helpful
Report
Reviewed in the United States on July 24, 2023
Harrowing and comprehensive history of Thalidomide. Very accessible-perhaps a little too much so. I enjoyed the style of the book, which depended a lot on various personal viewpoints, but I would have preferred footnotes to the notes section at the end of the book. Footnotes always make it easier for me to keep track of cites.
5 people found this helpful
Report
Reviewed in the United States on July 5, 2023
This book for me has been 61 years in the making. I am a character in the book — honestly, I really am. And so are a lot of my friends from U.S. Thalidomide Survivors, a nonprofit formed only a few years ago in 2018. This book is us. This book literally helped us find each other.

Can you imagine wondering all of your life why you look like all of the thalidomide survivors in Europe, and asking questions of doctors all your life, but being told that the FDA never approved the drug in our country, and it was never here? Can you imagine rewriting your history when you were in your late 50s? Finally learning the truth?

That is why I say this book will change history. It already is doing so. While it was previously mis-reported that the US escaped the thalidomide tragedy, this book shows us all that it did not. It introduces new information.

Jennifer Vanderbes illuminates the disturbing story of how thalidomide was handed out by United States drug companies, eager to get ahead of what they thought would be FDA approval (which never came) to doctors all across the country; who, in turn, gave it out to patients who often did not know what drug they were being given. This included pregnant women. This included my mother.

And her book goes on to show how US authorities, including the FDA, did not adequately investigate once the dangers of thalidomide were discovered. They did not track down the patients who had received it. They did not notify the unwitting victims and failed to find the babies affected.

Wonder Drug is a riveting read, so well-told and well-researched! The old statistics are out and the new ones are here. The casualties of this dark chapter in American history come to life in Jennifer’s book. I personally am proud she did our stories justice. Please read, share, and amplify this important new truth!
Customer image
5.0 out of 5 stars This book will change history!
Reviewed in the United States on July 5, 2023
This book for me has been 61 years in the making. I am a character in the book — honestly, I really am. And so are a lot of my friends from U.S. Thalidomide Survivors, a nonprofit formed only a few years ago in 2018. This book is us. This book literally helped us find each other.

Can you imagine wondering all of your life why you look like all of the thalidomide survivors in Europe, and asking questions of doctors all your life, but being told that the FDA never approved the drug in our country, and it was never here? Can you imagine rewriting your history when you were in your late 50s? Finally learning the truth?

That is why I say this book will change history. It already is doing so. While it was previously mis-reported that the US escaped the thalidomide tragedy, this book shows us all that it did not. It introduces new information.

Jennifer Vanderbes illuminates the disturbing story of how thalidomide was handed out by United States drug companies, eager to get ahead of what they thought would be FDA approval (which never came) to doctors all across the country; who, in turn, gave it out to patients who often did not know what drug they were being given. This included pregnant women. This included my mother.

And her book goes on to show how US authorities, including the FDA, did not adequately investigate once the dangers of thalidomide were discovered. They did not track down the patients who had received it. They did not notify the unwitting victims and failed to find the babies affected.

Wonder Drug is a riveting read, so well-told and well-researched! The old statistics are out and the new ones are here. The casualties of this dark chapter in American history come to life in Jennifer’s book. I personally am proud she did our stories justice. Please read, share, and amplify this important new truth!
Images in this review
Customer image
Customer image
58 people found this helpful
Report

Top reviews from other countries

Utpal
4.0 out of 5 stars nice
Reviewed in India on August 5, 2023
liked
Reading is for fun
5.0 out of 5 stars 60 years on & truths still coming to light
Reviewed in the United Kingdom on July 24, 2023
I congratulate the author for bringing this important issue to the public's mind and highlighting the challenges faced by US survivors. I work with a UK thalidomider and this subject therefore is very close to my heart. I felt the book was very thorough, dealt with the issues in a sensitive and highly informative way and I hope it gets the publicity it deserves so that politicians start to take notice.

It is a shocking read and it's high time that politicians started to take the issues seriously. These people are now facing huge living costs as their needs start to increase and they need justice and compensation.